Basic knowledge Flashcards

1
Q

3 systemic factor that impaired wound healing

A
  • Increasing age
  • Malnutrition
  • Diabetes
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2
Q

Describe serosanguineous fluid

A
  • Discharge that contain both blood and a blood serum
  • Due to damaged capillary
  • Old dressing might damaged the capillary close to skin when pulling off
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3
Q

Normal urine output

A
  • 800 to 2000ml per day if intake around 2 liter per day
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4
Q

How long did it take for Vit K to correct INR

A
  • IV route: onset within 2 hours
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5
Q

Nutritional status assessment

A
  • Unintentional weight loss
  • Body mass index (BMI)
  • Bitemporal wasting
  • Mid-arm circumference
  • Triceps skinfold thickness
  • Serum albumin (half-life: 18-20 days), transferrin (half-life: 8-9 days; indicator of protein status only in setting of normal serum iron)
  • Electrolyte, glucose, and BUN/Cr to assess fluid volume status before parenteral nutrition given
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6
Q

Definition of refeeding syndrome

A
  • The clinical complications that can occur as a result of fluid and electrolyte shifts during aggressive nutritional rehabilitation of malnourished patient
  • Potentially fatal when not detected/ treated early
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7
Q

Pathogenesis of refeeding syndrome

A
  • Hypophosphatemia: stores of phosphate depleted during starvation; when nutritional replenishment, glucose cause insulin release, which trigger cellular uptake of phosphate -> tissue hypoxia, myocardial dysfunction, inability for diaphragm to contract, rhabdomyolysis, hemolysis, seizure
  • Hypokalemia: c/b insulin same as above
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8
Q

Which access to choose for nutritional replenish

A
  • Typically do not start feeding parenterally before 1-2 weeks due to increase risk of infection in malnutrition patient (no added benefit as well comparatively) unless contraindicated for enteral nutrition (eg: bowel obstruction/ both hemodynamically unstable and have not had their IV volume fully resuscitated -> predisposed to bowel ischemia)
  • Central venous catheter if TPN given for more than few days because its high osmotic load is not tolerated by peripheral veins
  • Peripheral venous catheter rarely indicated due to lack of benefit from short term TPN and ease of obtaining central access
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9
Q

Type of NG tube feeding content

A
  • Standard
  • Concentrated: if required fluid restriction (eg: respiratory failure, volume overload)
  • Predigested: protein hydrolyzed to short-chain peptide, carbohydrate are in less complex form (eg: malabsorptive syndromes)
  • Critical illness: (eg: renal formula for patient with fluid and electrolyte restriction; glycemic control formula for patient receiving bolus feeding)
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10
Q

A-delta vs C nerve fiber

A

A-delta:

  • Pain (mechanical and thermal)
  • Myelinated, conduction speed fast

C:

  • Pain (mechanical, thermal and chemical)
  • Non-myelinated, conduction slow
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11
Q

Levels of sympathetic and parasympathetic outflow

A

> Sympathetic
- T1-L1

> Parasympathetic

  • CN 3, 7, 9, 10
  • S2-4
  • Cervical don’t have autonomic outflow
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12
Q

Sympathetic cardiac innervation at which level

A
  • T6

- So injury above might cause neurogenic shock

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13
Q

Triad of neurogenic shock

A
  • Bradycardia
  • Hypotension
  • Autonomic dysfunction (eg: hypothermia)
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14
Q

Location of baroreceptor

A
  • Carotid sinus

- Aortic arch

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15
Q

Total blood volume

A

5L

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16
Q

Definition of hypotension for child - Formula

A

<70 + 2*(Age of child)

17
Q

Definition for oliguria

A

Infants: <1 ml/kg/h
Children: <0.5 ml/kg/h
Adults: <400ml/day

18
Q

Causes of altered mental status

A

AEIOU TIPS

  • Acidosis
  • Electrolyte
  • Infection
  • Oxygen/ Opioid
  • Uremia
  • Trauma
  • Insulin (hypo/hyperglycemia)
  • Poisoning, Psychiatric
  • Stroke
19
Q

Formula for mean arterial pressure

A

[(2*DBP) + SBP] / 3

- DBP is multiplied by 2 because diastolic phase last longer than systolic phase

20
Q

2 local factors cause impaired wound healing

A
  • Infection

- Foreign body or contamination

21
Q

3 example of opioid agonist

A
  • Morphine
  • Codeine
  • Oxycodone
22
Q

3 systemic side effect of morphine

A
  • CNS depression
  • Nausea, vomiting
  • Respiratory depression
23
Q

Condition causing air under diaphragm

A
  • Hollow viscus perforation
  • Post-laparotomy
  • Vaginal insufflation for tubal pregnancy test
  • Entero-biliary fistula
24
Q

Classification of wound healing

A
  • Primary: occurs in wounds with dermal edge that are close together
  • Secondary: sides of wound not opposed, therefore healing occur from the bottom of the wound upwards
  • Tertiary: occurs when a wound is initially left open after debridement of all nonviable tissue
25
Q

Example of positive and negative acute phase reactants

A

> Positive

  • Procalcitonin
  • C-reactive protein
  • Ferritin
  • Fibrinogen
  • Hepcidin
  • Serum amyloid A

> Negative

  • Albumin
  • Prealbumin
  • Transferrin
  • Antithrombin
26
Q

Component of vital signs

A
  • Temperature
  • Blood pressure
  • Pulse rate
  • Respiratory rate
27
Q

Device for urinary retention other than CBD

A
  • External catheter (condom like device for men)