IBS

Question 1

Upper GI symptoms in IBS?

Answer 1

Between 25 and 50% of patients with IBS complain of dyspepsia, heartburn, nausea, and vomiting.

Question 2

رابطه IBS & dyspepsia?

Answer 2

Prolonged ambulant recordings of small-bowel motility in patients with IBS show a high incidence of abnormalities in the small bowel during the diurnal (waking) period; nocturnal motor patterns are not different from those of healthy controls.

The prevalence of IBS is higher among patients with dyspepsia (31.7%) than among those who reported no symptoms of dyspepsia (7.9%).

Conversely, among patients with IBS, 55.6% reported symptoms of dyspepsia.

In addition, the functional abdominal symptoms can change over time. Those with predominant dyspepsia or IBS can flux between the two.

Although the prevalence of functional GI disorders is stable over time, the turnover in symptom status is high. Many episodes of symptom disappearance are due to subjects changing symptoms rather than total symptom resolution.

Question 3

مکانیسم های پاتوفیزیولوژی IBS?

Answer 3

1-abnormal gut motor

2-visceral hypersensitivity

3-central neural dysfunction

4-psychological disturbances,

5-mucosal inflammation,

6-stress

7-luminal factors such as bile acid malabsorption and gut dysbiosis

8-Abnormal Serotonin Pathways

Question 4

What is post-prandial pain in IBS related to؟

مربوط به کدوم پاتوفیزیولوژی عه؟

Answer 4

ررر

Question 5

Which test suggests of visceral afferent dysfunction in IBS?

Answer 5

اا

Question 6

Ddx of Gastric and esophageal hypersensitivity? ۳

Answer 6

Gg

Question 7

اثر غذای پر از چربی در علایم بیماران IBS?

Answer 7

Gg

Question 8

کدوم علایم IBS منشا پاتوفیزیولوزی شون central?

۳

Answer 8

اتت

Question 9

تجربه ی یک Physical abuse چجوری ممکنه منجر به IBS شه؟

Answer 9

Hhh

Question 10

Post infectious IBS

بیشتز در چه گروهی لز بیماران رخ میده؟

Answer 10

اا

Question 11

What are the risk factors for developing postinfectious IBS? 8

Answer 11

Hh

Question 12

What is the risk factor for IBS in patients with age older than 60 years?

Answer 12

Gg

Question 13

عفونت GI با کدوم باکتری ها ممکنه منجر به IBS شه؟ ۳

Answer 13

لا

Question 14

مکانیسم احتمالی اسهال در IBS-D?

Answer 14

Increased intestinal permeabilityدر ۳۹ درصدشون مشاهده شده

در دسته ی : Immune activation and mucosal inflammation

Question 15

محرک تغیرر Permeability روده در IBS?

Answer 15

stress and anxiety

Question 16

چه تستی رو درIBS وقتی میخوایم ببینیم BOS داره یا نه انجام میدادیم؟
ایا نتیجه ش مطابقه با مطالعات دبگه؟

Answer 16

ااا

Question 17

افزایش ترشح سروتونین در کولون در IBS با چه علایمی مرتبطه؟

Answer 17

غغب

Question 18

Which clinical features are suggestive of IBS? 5

Answer 18

Ccc

Question 19

وجود چه علایمی به ضرر تشخیص IBS اند؟ ۵

Answer 19

تتت

Question 20

Ddx of IBS When pain is in the epigastric or peri umbilical area? 5

Answer 20

Biliary tract disease

PUDs

Intestinal ischaemia

Carcinoma of stomach and pancreas

Question 21

Ddx of IBS When pain is in the Lower abdomen?

Answer 21

Ggg

Question 22

اگه بیماری اومده با درد Post prandial pain accompanied by bloating nausea and vomit به چیا فکر مبکنیم؟

Answer 22

رذ

Question 23

Ddx

وقتی که اسهال علامت اصلی عه؟ ۷

Answer 23

ااا

Question 24

برای بیماری که Constipation dominant است چیارو باید اول R/O کنیم؟ 7

Answer 24

الا

Question 25

What is porphyria?

Answer 25

The porphyrias are metabolic disorders caused by altered activities of enzymes within the heme biosynthetic pathway.

Question 26

چه W/U هایی رو برای بیماری که مشکوکیم به IBS انجام میدیم؟ ۳

Answer 26

الا

Question 27

What do we do in patients with persistent diarrhoea not responding to simple anti-diarrhoeal agents?

Answer 27

Fff

Question 28

برای بیماران بالای ۴۰ سال که مشکوکیم به IBS از چه مدالیته Imaging استفاده میکنیم؟

Answer 28

للل

Question 29

Which w/u we do if the main symptoms are diarrhoea and increased gas?

Answer 29

Ggg

Question 30

Which w/u we do if the patient has excessive gas with bloating?

Answer 30

Fff

Question 31

اگر در IBS-D ها شک داریم به Coeliac sprue، چه وورک اپی انجام میدیم که مطمین شیم؟

Answer 31

الا

Question 32

اگر در بیماری که مشکوکیم به IBS، همزمان علامتای Dyspepsia رو ببینیم، اقدام بعدی؟

Answer 32

ااا

Question 33

اگر در بیماری که مشکوکیم به IBS، Post prandial right upper quadrant pain داشته باشه، اقدام بعدی؟

Answer 33

الا

Question 34

کدوم یافته های ازمایشگاهی به ضرر IBS اند؟ ۵

Answer 34

الا