Radioprotectors Flashcards
1
Q
Dose Reduction Factor
A
Dose of radiation with the drug / Dose of radiation without the drug
2
Q
Radioprotectors
A
Chemical compounds that provide protection against the effects of sparsely ionizing x-ray and gamma radiation through free-radically scavenging or hydrogen atom donation at sites of DNA damage
3
Q
Effectiveness of radioprotectors vs. LET
A
Effectiveness decreases as LET increases
4
Q
3 Prominent Radioprotection Compounds
A
WR-638 Cystaphos
WR-2721 Amifostine
WR-1607 d-CON (rat poison)
5
Q
Amifostine
A
Only radioprotective drug approved by FDA for use in radiation therapy under the trade name Ethyol
6
Q
Radioprotectors must be provided before/during/after exposure?
A
Before
