Exam Questions

Question 1

A pharmaceutical company creates a new beta 1 andrenoreceptor agonist. What physiological response will this drug reproduce?

Answer 1

Increase in heart rate

Question 2

What is the immediate espouse to the binding of an agonist to a G-proteins coupled receptor?

Answer 2

Alpha subunits binds to GTP instead of GDP

Question 3

To increase the Everton of an acidic drug with pKa of 4 a doctor prescribes a patient to drink a solution with pH 9.0. What is the most likely reason for this?

Answer 3

To increase ionisation of the drug

Question 4

What is the role of oligodendrocytes in neurotransmission?

Answer 4

Enhance the speed of the action potential

Question 5

What best describes the consequences of phase II drug metabolism

Answer 5

Increased water solubility

Question 6

What best describes a drug that acts as a partial agonist?

Answer 6

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Question 7

Ligand gated ion channels receptors can be e fined by the assembly of several protein. What proteins are assembled to form one of these receptors?

Answer 7

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Question 8

What molecule decreases upon stimulation of a Gq linked G-protein coupled receptor?

Answer 8

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Question 9

What mechanism is involved with the contraction of smooth muscle?

Answer 9

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Question 10

The sympathetic and parasympathetic nerves form two branches of autonomic nervous system. What is a major difference between the two systems?

Answer 10

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