Misc

Question 1

Give 2 examples of drugs which are prescribed by brand name

Answer 1

• Tacrolimus

- Lithium

Question 2

What is meant by pharmocokinetics?

Answer 2

What the body does to the drug. This includes absorption, distribution, metabolism and elimination.

Question 3

What is meant by pharmacodynamics?

Answer 3

What the drug does to the body.

Question 4

What is the mnemonic to remember which drugs should be stopped before surgery?

Answer 4

I LACK OP:

• Insulin (T2DM)
• Lithium
• Anticoagulants/antiplatelets
• COCP/HRT
• K sparing diuretics
• Oral hypoglycaemics
• Perindopril (and other ACE inhibitors)

Question 5

Which drug should be increased during/after surgery?

Answer 5

Long term steroids (“sick day rules” = double the dose)

Question 6

Specifically when would you stop lithium prior to surgery?

Answer 6

Day before

Question 7

Specifically when would you stop potassium sparing diuretics prior to surgery?

Answer 7

Day of surgery

Question 8

Specifically when would you stop ACE inhibitors prior to surgery?

Answer 8

Day of surgery

Question 9

Specifically when would you stop COCP/HRT prior to surgery?

Answer 9

4 weeks before

Question 10

Specifically when would you stop clopidogrel prior to surgery?

Answer 10

7 days before

Question 11

What is the maximum RATE of IV infusion of potassium?

Answer 11

IV potassium should not be given at more than 10 mmol/hour

Question 12

Which antiemetic must be avoided in Parkinson’s disease?

Answer 12

Metoclopramide (dopamine antagonist)