Electrophilic Aromatic Substitution Flashcards
1
Q
What is electrophilic aromatic substitution???
A
A reaction of an aromatic ring where the electrophile substitutes for a hydrogen atom.
2
Q
What are examples of aromatic drugs???
A
Metoclopramide
Ibuprofen
Aspirin
Proparacaine
3
Q
What are the two ways that electrons may be donated or withdrawn from the aromatic ring???
A
Inductive effects - effect on bond polarity which are through sigma bonds.
Resonance effect - Alters the electron distribution in a aromatic ring which are through pi bonds.
