Learn this pls - Antibodies Flashcards
IgA
- where found? (3)
- role?
- shape??
- how common?
- contains?
IgA
- where found: mucusoal areas: gut, resp. tract and urogential tract
- role: prevents colonisation by pathogens. causes agglunation of them and they get washed out
- shape: dimer
- how common; 2nd most common
- contains: j chains
IgD
- role?
- shape??
- how common?
- contains?
IgD
- role: antigen receptor on B cells that have not been exposed to antigens. activates basophils and mast cells = make antimicrobrial factors
- shape: monomer
- how common: very low levels
IgE
- role?
- shape??
- how common?
IgE
- role: binds to allergens !!! triggers histamines release from mast cells and basophils. protects agaisnt parastic worms
- shape: monomer
- how common: least common in serum
IgG
- role?
- shape??
- how common?
IgG
- role: Provides the majority of antibody-based immunity against invading pathogens
- shape: monomer
- how common: most common ! 75% of all Ig
IgM
- role(2)?
- shape??
- how common?
IgM
- role:
- expressed on the surface of B cells (monomer) and in a secreted form (pentamer) with very high avidity.
- Eliminates pathogens in early stages of B cell-mediated (humoral) immunity before there is sufficient IgG.
- shape: monomer or pentamer
- how common: 3rd most common
which antibody protects agaisnt parasitic worms?
IgE
which Ig is 1st to be made?
IgM
which Ig is the only antibody capable of crossing the placenta to give passive immunity to the fetus.?
IgG
which Ig found in breast milk?
IgA
which Ig mediates allergy response to release histamines?
IgE
