others

Question 1

clinical manifestation in neuroblastoma:

Answer 1

weight loss
abdominal distension
neuro:weakness, paralysis, bladder/bowel dysfunction
thoracic: chest pain SOB

Question 2

complication of diabetes mellitus ( long term):

Answer 2

• Diabetic retinopathy
• Diabetic nephropathy
• Angiophathy of lower extremities
Diabetic neuropathy
reduced joint motility
lipodystrophy

Question 3

Extra articular manifestation in juvenile rheumatoid arthritis :

Answer 3

salmon-pink rash
High swinging fevers
Enlarged lymph nodes
Weight loss
Joint inflammation and pain
Splenomegaly
Muscle pain
Pleuritis and pericarditis

Question 4

Clinical manifestation in asthma:

Answer 4

Diurnal variability, typically worse at night and early morning, changes with seasons, worse after excercise
Dry cough with wheeze and shortness of breath
A history of other atopic conditions such as eczema, hayfever and food allergies
Family history of asthma or atopy
improve with bronchodilators

Question 5

Diagnosis of agammaglobulinemia

Answer 5

X linked- so history of affected males in the family

Serum IgG , IgM,IgA low
Test for natural antibodies to A and B RBC antigens is abnormal
Tests for antibodies to routine vaccines abnormal
Flow cytometry- decrease b cells
Bone marrow- normal number of pre b cells