depot injections Flashcards
1
Q
long acting injectables have what kind of drug release profile
A
• Predictable drug-release profile during defined period of time
2
Q
do long acting injectables have good patient compliance
A
yes
3
Q
do long acting injectables have easy application
A
yes
4
Q
what do long acting injectables avoid
A
first pass metabolism
5
Q
advantages of SC
A
greater surface are for target injection sites, use of shorter needles, ease of self-administration, less discomfort, better safety profile – primary route for delivery of protein-based drugs – the volume of SC injection are usually limited to no more than 1-2 mL
6
Q
types of long acting injectable formulaitons
A
- oil based solution
- drug suspension
- polymer based
7
Q
what are oil based solution suitable for
A
- steroid esters
- IM route
