Tt vragen

Question 1

mycobacterial outer membrane is

fundamentally different from the Gram-negative outer membrane.Name 3 of these differences (5p)

Answer 1

mycobacterial OM is thicker
peptidoglycan linkage is different
the diffusion is different, MOM is difficult to penetrate

Question 2

Describe how the Type VII secretion machine functions as a one-step or two step secretion
system, considering the known and unknown components and the special mycobacterial outer
membrane. (

Answer 2

complex appears to stretch over whole envelope, but one component is active at
periplasmic side of membrane
could be either one-step or two step