Angina Flashcards
Chronic stable angina
- chest pain that occurs intermittently over a long period with a similar pattern of onset, duration, and intensity of symptoms
- manifestation of coronary artery disease (CAD)
- caused by inadequate oxygen supply to the myocardial cells.
Silent ischemia
- ischemia occurs in the absence of any subjective symptoms.
- Associated with diabetic neuropathy
*ischemia = lack of blood flow to area
Nocturnal angina
Occurs only at night but not necessarily during sleep
Prinzmental’s (variant) angina
- due to vasospasm NOT occlusion
- chest pain that occurs at rest (normally between midnight and the morning)
- usually in response to spasm of major coronary artery
- Seen in clients with a history of migraine headaches and Raynaud’s phenomenon.
- Spasm may occur in the absence of CAD
- May occur during REM sleep
myocardial ischemia
- when blood flow to the heart muscle (myocardium) is obstructed by a partial or complete blockage of a coronary artery by a buildup of plaques
- insufficient blood flow to the myocardium through coronary arteries narrowed by atherosclerosis.
Angina, or chest pain
is a result of reversible myocardial ischemia that occurs when the demand for myocardial oxygen exceeds the ability of the coronary arteries to supply the heart muscle with oxyge
Microvascular angina
- occurs in the absence of significant coronary atherosclerosis or coronary spasm
- happens because of problems in the small blood vessels bringing oxygenated blood to the hea
- chest pain is related to myocardial ischemia associated with abnormalities within the walls of small arterial blood vessels, which decrease blood flow to the heart, resulting in chest pain
Short-acting nitrates: sublingual nitroglycerine
• dilating peripheral blood vessels, coronary arteries, and collateral vessels.
Long-acting nitrates
• can be used to reduce the frequency of angina.
β-Adrenergic blockers
- by blocking the effects of the hormone epinephrine, also known as adrenaline. Beta blockers cause the heart to beat more slowly and with less force, which lowers blood pressure.
- reduce myocardial oxygen demand by decreasing myocardial contractility, HR, systemic vascular resistance (SVR), and BP.
Calcium channel blockers
- used if β-adrenergic blocking agents are contraindicated, are poorly tolerated, or do not control symptoms.
- preventing calcium from entering the cells of the heart and arteries.
- Calcium causes the heart and arteries to squeeze (contract) more strongly.
- By blocking calcium, calcium channel blockers allow blood vessels to relax and open.
Angiotensin-converting enzyme inhibitors
- result in vasodilation and reduced blood volume
- can prevent or reverse ventricular remodeling.
- prevent an enzyme in the body from producing angiotensin II, a substance that narrows blood vessels.
angiography
the x-ray visualization of the internal anatomy of the heart and blood vessels