11 - Higher functions of the brain Flashcards

1
Q

What is the function of the cortical association areas?

A

Receive, integrate and analyse signals from multiple cortical and subcortical regions. Output produces the complex human behaviours which make up our individuality.

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2
Q

What are the short range fibres called and what do the run between?

A

Arcuate fibres

Between gyri and adjacent lobes

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3
Q

What are the long-range connections?

A

Superior longitudinal fasciculus
Arcuate fasciculus
Uncinate fasciculus
Cingulum

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4
Q

Describe the layers of the cortex

A

Six layers
1-3 = cortical association areas
4 = input (motor and sensory cortex, thalamus, brainstem)
5 = output
6 = output (hippocampus, basal ganglia, cerebellum, thalamus)

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5
Q

What association areas are found in the frontal lobe?

A

Found in dominant hemisphere (L usually)

  • personality
  • higher intellect
  • mood
  • social conduct
  • language
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6
Q

What will occur with frontal lobe lesions?

A

Personality and behaviours changesInability to solve problems

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7
Q

What association areas are found in the parietal lobe?

A
Dominant
- language
- calculation
Non-dominant
- visiospatial awareness (shapes and images)
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8
Q

What will occur with a parietal lobe lesion?

A

Attention deficits
Contralateral neglect syndrome
- do not notice things on side opposite to the lesion

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9
Q

What association areas are found in the temporal lobe?

A

Memory and language in the dominant hemisphere

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10
Q

What will occur in a temporal lobe lesion?

A

Recognition deficits

- prosognosia

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11
Q

Define prosognosia

A

Failure to recognise faces

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12
Q

What association areas are found in the occipital lobe?

A

Vision

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13
Q

What will occur in an occipital lobe lesion?

A

Superior/inferior homonymous quadrantopia

Homonymous hemianopia

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14
Q

What diseases cause global lesions?

A

Alzheimers

Cerebrovascular disease

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15
Q

What is the input area for language?

A
Wernicke's area
Connections to:
- primary auditory cortex
- primary visual cortex
Interprets written and spoken words
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16
Q

What is the output area for language?

A

Broca’s area

- forms language components and sends information to the motor cortex

17
Q

Describe Wernicke’s aphasia

A

Disorder of comprehension

  • cannot understand written or spoken word
  • have fluent, but unintelligible speech (jargon aphasia)
  • loss of mathematical skills
18
Q

Describe Broca’s aphasia

A

Difficulty with speech

Can understand but have poorly constructed sentences and disjointed speech

19
Q

What are the functions associated with the dominant hemisphere?

A

Processes information - language
Maths
Logic
Motor skills

20
Q

What are the functions associated with the non-dominant hemisphere?

A
Looks at the whole picture
Emotion of language
Music and art
Visiospatial
Body awareness
21
Q

What are the connections between the cerebral hemispheres?

A

Corpus callosum - anterior commisure
Posterior commisure
Hippocampal commisure
CC is main and largest connection

22
Q

Define decelartive memories

A

Statement of facts

23
Q

Define procedural memories

A

Process of performing actions

24
Q

Where are memories stored?

A

Different areas throughout the cortex

  • appropriate area for memory
    e. g. visual memory in the occipital cortex, music playing memory in the temporal cortex
25
Describe short term memory
Seconds to minutes | working memory
26
Describe long term memory
Up to a lifetime | Consolidation of short term memory
27
How does neuronal plasticity work?
Persistent activation of NMDA and mGluR1-7 leads to up-regulation of AMPA receptors Strong, higher frequency signals causes long term potentiation which is though to be the basis of long term synapse strengthening and learning
28
How do memories form?
Information arises from the senses and passes to the amygdala and hippocampus This forms the memories.