Urologic Cancer

Question 1

Common Type of Kidney cancer

Answer 1

renal cell carcinoma 85%

Question 2

risk factors for kidney cancer 5

Answer 2

Smoking* - #1 risk factor

Obesity*

Age – as we get older

Male

Genetics – family hx increases risk

Question 3

prognosis if kidney cancer metastasizes

Answer 3

Usually not found until cancer has traveled to distance site. If cancer has metastasized about 10% survival 5 year

Question 4

Clinical manifestations of renal cell carcinoma

Answer 4

EArly- none

Late -
CVA angle tenderness

Hematuria – cola appearance

Palpable abdominal mass

Question 5

Symptoms R/T to metastases

Answer 5

dyspenic

cough

bone pain

Question 6

Treatments of renal cell carcinoma

Answer 6

resistance to traditional chemo

surgery is usually required

Question 7

bladder cancer =

Answer 7

Fourth most common cancer in men

urothelial carcinoma >90%

Question 8

risk factors for bladder cancer

Answer 8

smoking

male

occupations with exposure to toxins

low fluid intake

Question 9

clinical manifestations of bladder cancer

Answer 9

early - hematuria

later -

Frequency
Urgency
Dysuria

Question 10

treatment for bladder cancer

Answer 10

Chemotherapy- depends on the stage!

Stage 1 = Intravesical chemo

Advanced stages = Systemic chemo

Question 11

Intravesical Therapy Vaccine =

Answer 11

BCG Vaccine (6-12wees)

Question 12

MOA of Intravesical therapy

Answer 12

stimulates a local inflammatory response

Question 13

adverse effects of BCG

Answer 13

Bladder irritation!

Risk of systemic infection (Especially in immunocompromised)

Question 14

patient instructions with intravesical therapy (BCG)

Answer 14

1. empty bladder
2. dwell time = 2 hours
3. change positions q 15 minutes

Question 15

safety precautions with intravesical therapy

Answer 15

No on immunocompromised, disinfect urine 6 hours after treatment