NSAIDs - session 22

Question 1

prostaglandins exert pain amplifying effects during which parts of the pain pathway?

Answer 1

Transduction
Modulation
Perception

Question 2

What subclass of NSAID is best to block pathological prostaglandin production?

Answer 2

COX 2

Question 3

What organs/systems can NSAIDs affect?

Answer 3

GI ulceration
Renal Injury
Hepatic Injury
Platelet function

Question 4

True or False: A patient that does not respond to one NSAID will not respond to a different NSAID

Answer 4

FALSE

Question 5

Which NSAIDs are approved in cats for post op pain?

Answer 5

Meloxicam & Robenacoxib

Question 6

What is Acetaminophen classified as?

Answer 6

Analgesic, not NSAID

Believed to act on the arachidonic prostaglandin

Question 7

How do antiinflammatorys work?

Answer 7

Prostaglandin synthesis inhibition in peripheral tissues

Question 8

What are signs of Acetaminophen toxicity in cats?

Answer 8

methemoglobinemia, Heinz body hemolysis, hepatic failure, swelling in distal limbs

Question 9

What is the MOA of Galliprant?

Answer 9

prostaglandin antagonist