274 - Cancer Prevention

Question 1

Chemoprevention for cervical cancer?

Answer 1

HPV vaccine

Question 2

What patient population would benefit most from cancer prevention treatment?

Answer 2

Population at high risk for cancer

Question 3

What is the initial step in cancer development?

Answer 3

Genetic mutation

Question 4

Critical issues about recommendations regarding cancer prevention drugs involve:

a. safety & tolerability
b. efficacy against established tumors
c. demonstration of survival benefit
d. cost.

Answer 4

a. safety & tolerability

Question 5

Are there any agents approved for cancer prevention in prostate cancer?

Answer 5

No

Question 6

What is the recommendation for chemoprevention of colon cancer?

Answer 6

Low dose aspirin only in people age 50-70 who also have CVD risk factors

Not recommended in older people; risk of hemorrhage

Question 7

What is the recommended agent for breast cancer prevention in:

• Premenopausal women:
• Postmenopausal women:

Answer 7

• Premenopausal women: Tamoxifen
• Postmenopausal women:
  
  • If uterus intact and osteoporosis: Raloxifene
  • If uterus intact and no osteoporosis: Exemestane

Question 8

The following statements about cancer prevention and treatment are true (pick all that apply):

a. Both employ molecular targeted therapy.
b. Only the effects of cancer treatment can be measured.
c. Risks of not intervening apply only to cancer treatment.
d. Treatment of metastatic cancer cures more patients than can be achieved with cancer prevention

Answer 8

a. Both employ molecular targeted therapy

Question 9

Aspirin for prevention of colon cancer should be considered in

a. all adults
b. individuals over age 50
c. all individuals at risk for cardiovascular disease
d. those aged 50-70 who have an increased risk of cardiovascular disease.

Answer 9

d. those aged 50-70 who have an increased risk of cardiovascular disease.
* Don’t use in everyone*