Obstructive And Restrictive Lung Diseases

Question 1

Obstructive Lung disease

Answer 1

Charactiized by increase in airway resistance

FEV1/FEV is less than 0.7,

Question 2

Restrictive Lung disease

Answer 2

Charactiized by reduced expansion of lung parenchyma and decreased total lung capacity
Both FEV1 AND FVC are reduced but ratio remains Norma

Question 3

Common obstructive diseases

Answer 3

Emphysema, chronic bronchitis, asthma, bronchiectasis

Question 4

Emphysema

Answer 4

Irreversible enlargement of airspaces distal to the terminal bdonchiole, pink puffers

Question 5

Classification of emphysema

Answer 5

Centriacinar
Panacinar
Paraseptal
Irregular

Question 6

Chronic bronchitis

Answer 6

Persistent productive cough>3 months, blue bloarlters

Question 7

Asthma classification

Answer 7

Atopic-Ige tye 1 hypersensitivity reaction, onset on childhood

Not atopic-no evidence of allergen sensitization

Drug induced-aspirin sensitive asthma

Occupational-

Question 8

Pathogenesis of asthma

Answer 8

IL4-stimulates class switching to IgE and promotes the development of the additional Th2 cells

IL5 - development and activation of eosinophils

IL5-enhances mucus secretion