impact of drugs and pain on sleep Flashcards
what is nociceptive pain and neuropathic pain
nociceptive pain is caused by tissue damage, generally time-limited whereas neuropathic pain is caused by damage to the neurones and it is chronic
what pathway is important in modulating pain perception
descending inhibitory pathway
what are the type of sensory nerves which receives stimuli
A delta fibres which are fast and myelinated
C fibres which are slow and unmeylinated
what is pain
unpleasant sensory and emotional experience associated with actual or potential tissue damage
what is pain influenced by
previous experience, beliefs, environment, psychological factor, social factors
Pain can be classified as…
acute, chronic, acute on chronic
what is acute pain
less than 6 weeks duration, often protective in response to stimuli, responds well to treatment
what is chronic pain
persists or recur for 3> months, difficult to treat, can represent
nerve problems
what are examples chronic secondary pain
- underlying disease for which pain is a symptom
- cancer pain
- neuropathic pain
what are yellow flags
people who are at an increased risk of developing chronicity or poor prognosis. This could be due to:
- beliefs and judgement
- emotional responses (worry and fear)
- pain behaviour: avoiding the pain
what is analgesia
type of pain medication can be used in opioid
what is an example of a simple analgesics
paracetamol
what are examples of strong and weak opioid analgesics
weak opioids: codeine
strong opioids: morphine
when is anti-depressant medication prescribed
for analgesic effects for neuropathic pain
what is the function of anti-epileptic medication?
what are the mechanisms of the two types of medication used?
reduces neuronal activity
gabapentin: blocks voltage-dependent ca2+ channels which decreases hyperactivity
carbamazepine: blocks voltage-dependent NA+ channels which decreases neuronal activity
