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enrp > Germ Cell Ovarian Tumors > Flashcards

Germ Cell Ovarian Tumors Flashcards

1
Q

What are the 4 subtypes of Germ Cell Ovarian Tumors?

A

Teratoma
Dysgerminoma
Yolk sac tumor
Choriocarcinoma

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2
Q

What are the 4 subtypes of Germ Cell Ovarian Tumors?

A

Teratoma
Dysgerminoma
Yolk sac tumor
Choriocarcinoma

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3
Q

At what ages do Germ Cell ovarian tumors arise?

A

0-25+

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4
Q

Most common benign germ cell tumor?

A

Mature cystic teratoma

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5
Q

Mature cystic teratomas are bilateral or unilateral?

A

Unilateral

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6
Q

What is a mature cystic teratoma comprised of?

A

Mature tissues from all embryonic cell layers

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7
Q

In what aged women do Immature malignant teratomas arise?

A

Prepubertal and young women

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8
Q

Immature malignant teratomas are comprised of what?

A

Tissues from all embryonic cell layers + immature neuroepithelium

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9
Q

Immature malignant teratomas are the same as mature teratomas except they also have what?

A

Immature neuroepithelium

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10
Q

Monodermal Teratomas are comprised of?

A

1 tissue type only

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11
Q

What are the 2 types of Monodermal Teratomas?

A
  1. Struma ovarii

2. Carcinoid tumor

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12
Q

Struma ovarrii monodermal teratoma

A

Mature thyroid tissue

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13
Q

Does Struma ovarii often cause the symptoms of hyperthyroidism?

A

NO

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14
Q

Carcinoid tumor monodermal teratoma

A

Carcinoid syndrome

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15
Q

What are the 3 symptoms caused by a carcinoid tumor monodermal teratoma?

A

flushing
diarrhea
hypotension

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16
Q

What is the most common malignant germ cell tumor?

A

Dysgerminoma

17
Q

Ovarian counterpart of a testicular seminoma

A

Dysgerminoma

18
Q

What mutation is present with dysgerminomas?

A

KIT mutation

19
Q

What do tumor cells secrete with Yolk Sac tumors?

A

Alpha fetoprotein (AFP)

20
Q

What tumor secretes AFP?

A

Yolk sac tumor

21
Q

What histo items will be present with Yolk Sac tumors? (2)

A

Schiller duval bodies

Hyaline droplets

22
Q

Schiller duval bodies and hyaline droplets are present with?

A

yolk sac tumors

23
Q

How do Choriocarcinomas act?

A

Aggressive

24
Q

What type of differentiation is present with Choriocarcinomas?

A

Placental (trophoblastic)

25
Q

What do Choriocarcinomas secrete?

A

B-HCG

26
Q

What tumor secretes B-HCG?

A

Choriocarcinoma

27
Q

What do Schiller Duval bodies look like and what are they present with?

A

Glomerulus

– yolk sac tumor

enrp (45 decks)

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