Insulins Flashcards

1
Q

What are some rapid acting insulin’s?

A

Lispro (Humalog)
Aspart (Novolog)
Glulisine (Apidra)

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2
Q

What does onset mean?

A

When the medication starts working

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3
Q

What does peak mean?

A

When the medication will achieve the greatest effect

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4
Q

What does duration mean?

A

How long the medication continues to work

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5
Q

What is the onset of Rapid Acting Insulin?

A

<15 minutes

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6
Q

What is the peak of Rapid Acting insulin?

A

30-90 minutes

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7
Q

What is the duration of rapid acting insulin?

A

3-5 hours

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8
Q

When mixing rapid acting insulin and intermediate acting insulin, what should be drawn up first? And why?

A

Rapid acting insulin (clear insulin) should be drawn up first when mixing with NPH (intermediate acting insulin) to avoid contaminating the rapid acting insulin with NPH

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9
Q

What are some types of short acting insulin?

A

Regular insulin

NovoLIN R or HumuLIN R

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10
Q

What is nutritional insulin and what is another name for this? What type of insulin is used as nutritional insulin? (Rapid, short, long, or intermediate?)

A

Insulin taken with meals to help body balance out to glucose levels due to spike in BG levels after eating.
It can also be referred to as “Prandial insulin”
This is a rapid acting and or short acting insulin

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11
Q

What is the onset of short acting insulin?

A

0.5-1 hour

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12
Q

What is the peak of short acting insulin?

A

2-4 hours

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13
Q

What is the duration of short acting insulin?

A

4-8 hours

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14
Q

What types of insulin’s are mixed with NPH? —Rapid, Short, or Long acting?

A

Both short acting and rapid acting insulin’s are mixed with NPH

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15
Q

What type of insulin’s are used as basal insulin’s?

A

NPH (intermediate acting) and long acting

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16
Q

What are some examples of intermediate acting insulin’s?

A

NPH (NovoLIN N or humuLIN N)

17
Q

What is the onset of intermediate acting insulin?

A

1-2 hours

18
Q

What is the peak of intermediate acting insulin?

A

4-10 hours

19
Q

What is the duration of intermediate acting insulin?

A

10-18 hours

20
Q

What is the generic name/trade name of insulin that can be used as nutritional or correctional insulin?

A

Aspart (Novalog) and Regular insulin (Novilin R or HumuLIN R)

21
Q

What is the generic name/trade name of insulin that is used as basal insulin?

A

Glargine (Lantus) or Detremir (levemir)

22
Q

What are some types of long acting insulin?

A

Glargine (Lantus) and Detemir (Levimir)

23
Q

What is the onset of Glargine?

A

1-2 hours

24
Q

What is the peak of Glargine

A

No peak

25
Q

What is the duration of Glargine?

A

20-24 hours

26
Q

What insulins cannot be mixed with other insulins?

A

Glargine (Lantus) and Detemir (Levemir)

27
Q

What do long acting insulin’s look like?

A

They are clear formulations

28
Q

What are some combination insulin examples?

A

NovoLIN 70/30
HumuLIN 70/30
Novolog mix 70/30
HumaLOG mix 75/25 or 50/50

29
Q

What is the onset of NovoLIN 70/30 and HumuLIN 70/30

A

0.5-1 hour

30
Q

What is the peak of NovoLIN 70/30 and HumuLIN 70/30

A

2-10 hours

31
Q

What is the duration of NovoLIN 70/30 and HumuLIN 70/30

A

10-18 hours

32
Q

What does the “70” and “30” mean in NovoLIN 70/30 and HumuLIN 70/30?

A

70% NPH and 30% regular

33
Q

What is the onset of NovaLOG mix 70/30 and HumaLOG mix 75/25 or 50/50

A

<15 minutes

34
Q

What is the peak of NovaLOG mix 70/30 and HumaLOG mix 75/25 or 50/50

A

1-2 hours

35
Q

What is the duration of NovaLOG mix 70/30 and HumaLOG mix 75/25 or 50/50

A

10-18 hours

36
Q

What is the peak of determir (levemir)

A

Relatively flat

37
Q

How long does Detemir (levemir) last (duration)?

A

Up to 24 hours

38
Q

How many peaks do combination insulin’s have? (Such as Novilin 70/30, HumuLIN 70/30, HumaLOG mix 75/25 or 50/50)

A

These have two peaks (1 peak from each formulation in the mixture of insulin)

39
Q

What does the the ratios represent in insulin combinations such as: Novolog 70/30, and Humalog 75/25 or 50/50

A

Novolog 70/30: 70% Aspart protamine 30% aspart

HumuLOG 75/25 or 50/50: 75% lispro protamine/ 25% lispro or 50% lispro protamine/50% Lispro