Sarcoidosis Flashcards
1
Q
what is it?
A
inflammatory condition - oresence of non-caseating granulomas (small patches of red,swollen tissue)
multi-systemic disease
2
Q
cause?
A
type 4 hypersensitivity reaction - T-cell mediated
3
Q
typical patient?
A
young, female with family history
4
Q
features of acute sarcoidosis?
A
swinging fever
polyarthralgia
erythema nodosum
5
Q
features of insidious sarcoidosis?
A
non-productive cough
SOB
fatigue
6
Q
other features?
A
uveitis
cervical and submandibular lymphadenopathy
lupus pernio (lupus type rash)
7
Q
diagnosis?
A
largely clinical
no single diagnostic test-
bloods, serum ca, ACE, CXR
CXR - used for staging - 0 to IV
8
Q
management?
A
- observation
- steroids - inhaled budesonide, oral prednisolone
- immunosupression - methotrexate, azathioprine
9
Q
complications?
A
resp - pulmonary HTN, resp failure, fibrosis
CV- cor pulmonale, heart block
CNS- cranial nerve palsies
ocular- uveitis, keratoconjunctivitis sicca
