Micro 3 - Hospital acquired infections

Question 1

define HAI

Answer 1

onset of infection >48h after hospital admission

Question 2

Organisms associated with Catheter associated BSI

Answer 2

MRSA
Yeast/candida
MSSA
resistant gram -ve

Question 3

Organisms associated with urinary Catheter associated UTI

Answer 3

MRSA
Yeast/candida
E.coli

Question 4

Organisms associated with ssi

Answer 4

MRSA

MSSA

Question 5

3 commonest HAI starting from the most common

Answer 5

HAP
SSI
UTI

Question 6

Which 3 drugs are responsible for C diff?

Answer 6

Clindamycin
Cephalosporins
Ciprofloxacin

Question 7

Mx of

c diff
recurrent c diff

Answer 7

vancomycin

fidaxomicin - used in patients who get recurrent c diff to prevent recurrence

Question 8

How does c. diff cause pseudomembranous colitis?

Answer 8

produces toxins

pro-inflammatory = inflammation
cytotoxic = cell damage
enterotoxic = gut damage

Question 9

Commonest organisms causing UTI in community + in the hospital

Answer 9

o Community: E.coli > S. saprophyticus > Proteus > Klebsiella

o Hospital: E. coli > Klebsiella > Proteus > Pseudomonas

Question 10

Which is one of the organism is responsible for SSI and what do we treat it with

Answer 10

MRSA

gram +ve

Vancomycin

Question 11

What is the Hospital microbiome project

Answer 11

determined which environmental parameters have the greatest influence on the development of microbial communities within a hospital