Modul 3, part 2

Question 1

Cardiovascular responses to fear

Answer 1

Increased atherosclerosis, increased cardiac ischemia, increased BP, decreased heart rate variability, increased MI, sudden death

Question 2

cardiovascular pathway of fear in brain

Answer 2

amygdala to locus coeruleus

Question 3

Memories are stored in what area of the brain?

Answer 3

hippocampus

Question 4

Loop in the brain associated with worry and obsessions

Answer 4

cortico-striato-thalamo-cortical circuit

Question 5

Reduces actions of benzos

benzo antagonist

Answer 5

flumazenil

Question 6

agonist for GABAa receptors

Enhances GABA effects

Answer 6

benzodiazepines

Question 7

targets GABAa receptors

Answer 7

Benzodiazepines
Sedatives
hypnotics
barbituates
alcohol

Question 8

5HT1A partial agonist used to treat anxiety

Answer 8

Buspirone (Buspar)

Question 9

Anxiolytic that takes weeks to take effect , like SSRIs

Answer 9

Buspirone (Buspar)

Question 10

works on serotonin on both postsynaptic and presynaptic areas

Answer 10

buspar

Question 11

excess norepinephrine symptoms

Answer 11

fear/panic

tremor, sweating, tachycardia, hyperarousal

Question 12

reduced stimulation of beta adrenergic receptors leads to. ____

Answer 12

decreased anxiety and associated symptoms

Question 13

Nonbenzodiazepine agonists

Answer 13

zolpidem (Ambien)
Zaleplon (Sonata)
eszopiclone (Lunesta)

Question 14

Rapid-acting benzos

Answer 14

Valium
Ativan
Xanax

Question 15

shorter half life but slower onset of action

Answer 15

lorazepam

Question 16

longer half life but produce more rapid but briefer action

Answer 16

Diazepam

Question 17

benzodiazepines used for insomnia (no more than 7-10 days) without thorough investigation of cause of insomnia

Answer 17

temazepam, flurazepam, triazolam

Sole purpose is insomnia