Endocrine Flashcards
Types of hypothyroidism
Primary (less T syn)
Secondary/central (less TSH)
Tertiary (less TRH)
Congenital (thyroid dysgenesis, thyroid dyshormogenesis)
a hyperthyroid medication that inhibits both thyroid peroxidase and 5’-deiodinase.
Propylthiouracil
Two hyperthyroidism medications that can cause agranulocytosis and aplastic anemia.
Propylthiouracil
Methimazole
Inhibition of thyroid peroxidase is the primary mechanism of action of
methimazole
Anterior pituitary hormones
GH Prolactin Gonadotropins(FSH + LH) ACTH TSH Melanocyte stimulating hormone(MSH)
Recombinant GH
Somatropin
Somatrem
GH deficiency
AIDS wasting
Hormone used to detect and distinguish between cushing’s disease and ectopic ACTH secretion
Corticotropin release hormone
Role of FSH
-females
Ovarian follicles development
Ovarian steroidogenesis
-males
Spermatogenesis regulation
Testosterone to estrogen in sertoli cells
Role of LH
-females
Ovarian steroidogenesis
Ovulation
-males
Testosterone production in leydig cells
Synthetic human GnRH
Gonadorelin
Other name for prolactin
Mammotropin
Lactogenic hormone
Effects of dopamine
Prolactin secretion(decrease)
Increase GH levels
Decrease GH in acromegaly
Parkinsonism relief
Nausea, vomiting(CTZ)
Hypotension
Uses of dopamine
Hyperprolactenemia
Acromegaly
Parkinsonism
Restless leg syndrome
Steps in synthesis of thyroid hormone
Iodine trapping Oxidation and iodination Coupling Hormone release Peripheral conversion of T4 to T3
Uses of thyroid hormones
Creatinism Myxoedema Myxoedema coma Benign thyroid nodule Thyroid carcinoma (papillary carcinoma)
