Peripheral blood films Flashcards
when would you see acanthocytes (spike cells)
liver disease
hyposplenism
when would you see basophillic RBC stippling
lead poisoning, megaloblastic anaemia, thallassaemia, myelodysplasia
when would you see Heinz bodies = denatured Hb inclusions in RBCs
G6PDD, CLD
when would you see howell-jolly bodies
= purple spot remnants in RBCs
post splenectomy/hyposplenism (SCD), megaloblastic anaemia
when would you see reticulocytes
inc in haemolytic anaemia, dec in aplastic anaemia/chemo
when would you see right shift of periph blood films
= hypermature white cells/hypersegmented polymorphs
megaloblastic anaemia, uraemia, liver disease
when would you see rouleaux
= stacks of RBCs
chronic inflam, myeloma
when would you see schistocytes
RBC fragments microangiopathic anaemia (DIC, HUS, TTP, preeclam)
when would you see spherocytes
heriditary sphero, AIHA
when would you see target cells on a peripheral blood film
liver D, hyposplenism, thall, IDA
