Hypothyroidism Flashcards
What is the most common type of Hypothyroiditis in Developed World
Hashimoto’s
What Antibodies associate with Hashimoto’s
Anti-TPO !!!!!!
Anti- Thyroglobulin
Anti-TSH (uncommon)
What are the auto-immune causes of Hypothyroidism
Hashimoto
Atrophic thyroiditis
What are the iatrogenic causes of hypothyroidism
Surgery
Radiation
Radioablation
What are the congenital causes of Hypothyroidism
Thyroid ablasia Pendred Syndrome(Thyroxine defect)
What are the iodine related causes of hypothyroidism
Infiltration
- Sarcoidosis
- Haemochromotosis
What are the peripheral features of hypothyroidism
Dry thick skin
Brittle hair
Loss of lateral third eyebrow
What are the head and neck features of Hypothyroidism
Macroglossia
Puffy face
Goitre
What are the cardiac features of Hypothyroidism
Bradycardia
Cardiomegaly
What are the neurological causes of Hypothyroidism
Carpal Tunnel syndrome
Slow reflex
peripheral neurpathy
What is the management of Hypothyroidism
1st = levothyroxine
Annual TSH check up
What is the changes in TSH, T3 and T4 between Primary and secondary causes of hypothyroidism
TSH-T3-T4
P= HIGH-LOW-LOW
S= ALL LOW
SC = HIGH - NORMAL -NORMAL
What are the investigations for Hypothyroidism
1st = Thyroid function test Bloods = Anti TPO/Anti-Thyroglobulin w/Anaemia
What is the most common cause of Hypothyroidism in developing world
Iodine defficiency
Postpartum Thyroiditis
What is Postpartum thyroiditis
Like HASHIMOTO BUT…..
- Acute after pregnancy
- Resolves alone
