Rheumatology Flashcards
What antibody is investigated in Scleroderma and is it diffuse or limited?
SCL-70 and Diffuse
What symptoms are present in Limited CREST and what antibody is being tested?
Calcinosis, raynaud’s, esophygeal dysmotility, sclerodactyly, telangiectasias. Centromere.
What is the diagnostic investigation for Rheumatoid arthritis?
Anti-CCP
What is Sjorgen’s disease? and what antibodies are tested?
SICCA - Dry eyes and mouth. Anti-SSA, Anti-SSB and RO/LA
In what condition do you find Livedo reticularis?
Polyarteritis Nodosa - Inflammation of the arteries, can lead to tissue necrosis.
What is the diagnostic test for Temporal Arteritis and it’s treatment?
Temporal Biopsy & Steroid
Intermittent 1 or 2 fevers a day with joint pain and stiffness in a child less that 16 years of age is known as?
Juvenile Rheumatoid Arthritis
Which rheumatoid condition causes muscle pain?
Polymyalgia Rheumatica
What condition causes Muscle Weakness and what how is it a) investigated? b) diagnosed?
Polymyoistitis - Electromyography and Muscle Biopsy
What is the difference between Reiter’s Syndrome and Septic Arthritis?
Reiter’s syndrome - Reactive arthritis - delayed response, usually three weeks after an infection in the body.
Septic Arthritis - Inflammatory response to an infection in a single joint.
What crystals are seen in Gout vs Pseudogout
Negative birefringent crystals (Rod shaped and needle) vs Positive birefringent crystals (rod-shaped with blunt ends).
If C3 and C4 are low, is that indicative of a controlled SLE?
NO - C3 and C4 are part of the immune system complement system. If it is low the disease is highly active.
What 3 conditions is someone susceptible to if they have the HLA-B27 gene?
Ankylosing spondylitis, Crohns, Reiter’s Syndrome
What condition is associated with 12 trigger points?
Fibromyalgia
