Biocompatibility Flashcards
What 4 categories can biomaterials be divided into?
- Inert
- Interactive
- Viable
- Replant
What are the 4 stages that occur in response to tissue injury?
- Hemostasis
- Inflammation
- Proliferation
- Remodelling
Key features of proliferative phase (4 things)
- Fibroblast migration
- Collagen synthesis
- Angiogenesis
- Contraction
What is the process of machrophages, neutrophils or giant cells internalising foreign bodies, pathogens and dead or dying cells?
Phagocytosis
What is the coordinated response by white blood cells to injury or infection?
Inflammation
What is the final phase of wound healing?
Remodelling
What is the active process of cellular breakdown and removal of biomaterial?
Resorption
What is the consequence of an implant being blocked off from surrounding tissue with fibrous tissue?
Encapsulation
When a material functions as designed without eliciting an unwanted response it is said to be …
Biocompatible
What is the type of white blood cell responsible for immediate response to a foreign body or injury?
Neutrophil
Biocompatibility must consider mechanical response to implant, surface compatibility and which other?
Chemical
Elicits no biological response
Inert
Larger particles are dealt with by macrophage cells forming…
Foreign Body Giant Cells (FBGCs)
