07-VASCULAR PATHOLOGY

Question 1

Large vessel vasculitis?

Answer 1

involves aorta or its major branches.
01-temporal giant cell arteritis
02-Takayasu arteritis

Question 2

Temporal giant cell arteritis?

Answer 2

common in older adults> 50 yrs usually female
classic location: branches of 2carotid arteries
CHARACTERSTIC FEATURE: High ESR > 100 mm

Question 3

symptoms of temporal arteritis and investigation and treatment

Answer 3

headache
visual disturbances
jaw claudication
muscle pain (polymyalgia rheumatia)
investigation on biopsy
treatment with corticosteroids
IF SUSPECT TEMPORAL ARTERITIS GIVE CORTICOSTEROIDS

Question 4

TAKAYASU ARTERITIS

Answer 4

granulomatous vasculitis < 50 yrs young asian female
INVOLVES AORTIC ARCH AT BRANCH POINTS.
ESR high
visual neurologic symptoms
PULSELESS DISEASE
give corticosteroids

Question 5

Middle vessel vasculitis?

Answer 5

involves muscular arteries that supply organs
01-polyarteritis nodusa
02-kawasaki disease
03-beugers disease

Question 6

polyarticular nodosa

Answer 6

necrotizing vasculitis
LUNGS ARE SPARED
in young adults
different signs depending upon organ effected

Question 7

symptoms, labs, treatment of polyarteritis nodosa

Answer 7

hypertension if renal artery
abdominal pain with melena if mesenteric artery
skin lesions.
Serum HBsAg associated.
SRTINGS OF PEARLS APPEARANCE
give corticosteroids and cyclophosphamide.

Question 8

kawasaki disease?

Answer 8

Involves coronary artery
affects asian children <4 yrs
very vague symptoms: fever , conjuctivitis ,erythematous rash on palms and soles , enlarge cervical lymph nodes. 
GIVE ASPIRIN AND IV ig.
self-limited

Question 9

buerger disease?

Answer 9

necrotizing vasculitis
PRESENTS WITH ULCERATION OF FINGERS AND TOES.
HIGHLY ASSOCIATED WITH SMOKING.
TREATMENT: STOP SMOKING