Antibodies Flashcards
What is the most abundant Ig found in blood
IgG
what is the functions of IgG
- opsonises/neutralises
- only one that crosses placenta to provide passive immunity
- Targets virus/bacteria
where is IgA found
present in secretions such as tears, saliva, mucus, and breast milk
monomeric from in blood
functions of IgA
- defence of mucous membranes esp. gut
- present in breast milk
- confers passive immunity on nursing infant
- targets virus / bacteria
what is the first Ig class produced after initial exposure to antigen
IgM
Where is IgM expressed
On naïve B cells
function of IgM
Very effective in activating complement
Targets extracellular bacteria
Acts as antigen receptor (BCR)
where is IgE present
in blood at low concentrations
What are IgEs functions
immunity to multicellular parasites
Allergic reactions
which antibody causes allergies
IgE
where is IgD expressed
on Naïve B cells
What are IgD functions
acts as antigen receptor (BCR)
the specific function is unknown
which two antibodies act as antigen receptors
IgM, IgD
