geriatric pharma

Question 1

<21

Answer 1

paedatric

Question 2

> 65

Answer 2

geriatric

Question 3

<1 month

Answer 3

neonates

Question 4

1m - 2 years

Answer 4

infants

Question 5

2 yrs - 12 yrs

Answer 5

child

Question 6

12-21 years

Answer 6

adolescent

Question 7

what 4 things does drug absoprtion depend on?

Answer 7

blood flow at site of action
rectal absorption
transdermal absorption
GI function

Question 8

what may cause cv shock and vasoconstriction in neonates?

Answer 8

anticonvulsants
sympathomimetic agents
antibiotics

Question 9

higher membrane permeability (BBB) may result in what?

Answer 9

kernicterus aka brain damage

Question 10

what do glucocorticoids do?

Answer 10

affect growth and development bc they cause early fusion of epiphysis

Question 11

how to calculate dose based on age

Answer 11

adult dose x age / age + 12

Question 12

how to calculate dose based on weight

Answer 12

adult dose x weight / ( 70 if kg and 150 if lbs)

Question 13

how to calculate dose based on surface area ( most accurate)

Answer 13

adult dose x SA of child in m^2 / 1.7

Question 14

Cockcroft Gault formula ( age 40-80)

Answer 14

creatinine clearance ( ml/min) = (140-age) x weight in kg / 72 x serum, creatinine in mg/dL

for women x 0.85. ( bc reduced. muscle mass)

Question 15

in elderly there is a decrease in response of what receptor agonists>?

Answer 15

beta adrenoceptor agonists

Question 16

what is less effective in old people

Answer 16

b1 agonists

Question 17

what are olde people more sensitive to ?

Answer 17

cns depressants