Fracture Healing Flashcards

1
Q

Days 1 - 5

A

Hematoma formation

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2
Q

Days 5 - 11

A

Fibrocartiliganous callus formation

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3
Q

Days 11-28

A

Bony callus formation

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4
Q

Day 18 onwards

A

Bone remodeling

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5
Q

During hematoma formation what cytokines are released?

A

TNF alpha

BMPs

IL 1 6 11 23

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6
Q

What drives differentiation of mesenchymal stem cells into fibroblasts chondroblasts and osteoblasts?

A

BMPs

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7
Q

What stimulates further differentiation of the chondroblasts chondroclasts osteoblasts and osteoclasts ?

A

RANK - L

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