CYP Flashcards

1
Q

Inhibitors

A
Azole Antifungals (fluconazole, Posaconazole)
Clarithromycin/Erythromycin
Diltiazem/Verapamil
Amiodarone/Dronedarone
Fluvoxamine/Nefazodone
Grapefruit Juice

Inhibit the enzyme so the concentration of drug increases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Inducers

A
Carbamazepine/Oxcarbazepine/Eslicarbazepine
Phenytoin/Fosphenytoin
Phenobarbital/Primidone
Rifampin
St John’s Wort

Speeds up the enzyme = less concentration of drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly