Cardiac Disease Flashcards

1
Q

Who III disease- 5 examples.

A
Mechanical valve
Systemic right ventricle
Fontan circulation
Cyanotic heart disease
Aortic dilatation 
(40-45 marfan’s, 45-50mm other)
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2
Q

Who IV cardiac disease- 5 examples

A
Pulmonary arterial hypertension
LVEF <30% or NYHA 3-4
Previous ppcm, residual lv imp
Severe aortic/mitral stenosis
Aortic dilatation 
(>45mm marfans, >50mm other)
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3
Q

Who class II cardiac disease-

A
Repaired TOF
Most arrhythmia
Asd’s or vsd’s unrepaired
Mild lvef
HCM
Bicuspid aorta <45mm
Marfans, no dilatation
Native or tissue valve
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4
Q

Who class I cardiac disease- 5 examples

A
Pulmonary stenosis
Mitral valve prolapse
PDA
Ectopic beats
Repaired simple lesions
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5
Q

Maternal mortality rate pulmonary hypertension?

A

10-25%

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6
Q

Lesions leading to PAH?

A

ASD/VSD (Eisenmenger’s syndrome) with PAH
chronic thromboembolic disease
lung disease (CF)
connective tissue disease (SLE)

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7
Q

Medications often required antenatally for PAH?

A

phosphodiesterase inhibitors (sildenafil), NO/prostanoid analogues, diuretics, thromboprophylaxis

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8
Q

PAH. Recommendations regarding

  • mode of delivery,
  • fluid balance in labour,
  • uterotonics
  • positioning
A

no evidence re LSCS vs. NVD
avoid hypovolaemia, systemic vasodilatation, maintain preload.
avoid syntocinon and regional analgesia causing vasodilatation
avoid supine positioning

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9
Q

High risk congenital heart lesions?

A

transposition
systemic RV
uni-ventricle defects
fontan circulation

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10
Q

Labour considerations patent ductus arterioles?

A

avoid hypotension i.e. epidural, spinal, syntocinon, PPH

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11
Q

Risk of VSD in offspring with maternal VSD?

A

10-15%

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12
Q

When might ASD/VSD deteriorate?

A

left to right shunt with PPH/reduced preload.

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13
Q

Effect on pregnancy of maternal congenital cyanotic disease?

A

cyanosis –> polycythemia –> VTE
hypoxia –> misc, SB, fetal growth restriction, PTB
pulmonary hypertension high mortality

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14
Q

Mitral stenosis. Effect of pregnancy on disease?

A

graded by velocity of blood flow across valve area.
velocity increases, therefore grading often worsens during pregnancy
increased risk of AF due to left atrial stretch.
Increased risk of clot formation left atria.

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15
Q

Management of mitral stenosis in labour?

A

fluid balance
avoid supine/sithotomy
treat pulmonary oedema
rate control (metoprolol)

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16
Q

Mortality and recovery of LV function in PPCM?

A

2% mortality
28% full recovery of LV function

if pregnant again with residual impairment
44% develop HF

17
Q

Risks of thrombosis with LMWH and warfarin with mechanical valves?

A

5-7% LMWH (2-3% maternal death)

2-3% warfarin (0.9% maternal death)

18
Q

When can warfarin cause embryopathy or fetopathy?

A

embryopathy = 6-12 weeks (not dose dependent)

fetopathy = 12-40 weeks (increased ICHH, INR in fetus can be 2-4x that of mother, dose dependent)

19
Q

Inheritance of Marfan’s syndrome?

A

autosomal dominent

2-3/10,000 affected.

20
Q

Change in cardiac output immediately PP?

A

rises 60-80%, rapid decline to pre labour values within 1 hour.

21
Q

Uterotonics with mitral stenosis?

A

Oxytocin- IM only. Can cause pulmonary vasoconstriction, systemic vasodilation. Avoid IV.

ergometrine and carboprost- cause pulmonary and systemic vasoconstriction with may overload impaired ventricles

PR misoprostol is safe

22
Q

Analgesia considerations mitral stenosis?

A

epidural- low dose to minimise haemodynamic instability.

23
Q

Management of second stage with mitral stenosis?

A

passive second stage, operative vaginal delivery.

24
Q

warfarin embryopathy features?

A

nasal hypoplasia

skeletal abnormalities

25
Q

Cardiac conditions with mortality of 15% or more in pregnancy?

A
mechanical valve thrombosis
any WHO class IV disease