Gastro Flashcards

1
Q

what gets absorbed

in distal ileum

A

B12, Bile

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2
Q

Folic acid gets absorbed

in

A

First part of intestine

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3
Q

What gets aAbsorbed from proximal as well as distal si

A

GIucore
AA
Lipids

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4
Q

Mined anemia may occur

due to malabsorption in

A

Proximal ?

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5
Q

order of sequence absorption of fat

A

TG → Fat globules → ED → FA → micalle → enterocyte → FA → TG → chylomicrons → lymph → blood →

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6
Q

Bacterial overgrowth synchome

A

conj bile→ un conj bile

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7
Q

Causes of fat malabsorption

A
Decreased bile
Decreased lipase
 Mucosal disease of intestine
Decreased chylomicrons
lymphangiectasia
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8
Q

Ix Fat malabsorption

A

72 hour sfool fat
Steatorrea > 7 g/ dy
spot test
Breath test

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9
Q

Triglyceride used for breath test

A

tripalmitin
triolain
tri octaneon

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10
Q

Monosacharides in
intestine alesorbed
by

A

SGLT -1(glucose and galactose )

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11
Q

Fructose transporter

A

GLUT_ 5

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12
Q

D- Xylose is a test of

A

mucosa of proximal SI
25g show wine
<4.5 g positive test

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13
Q

False positive d- xylose test

A

Pyloric
stenosis
Renal failure
Third space shifting

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14
Q

R- Binder

A

Transcobalamine
haptocorin
Vit B 12 alesorption
secreted by salivary glands

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15
Q

Cubulin receptors

found in

A

Distal SI

IF receptors

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16
Q

Role of pancreatic enzymes

in Vit B12 absorbtion

A

Breaks down

transcobalamin + vit B12

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17
Q

C auses of malabsorption Vit B12

A

Pernicious Anemia
Pancreatic diseases
Diseases of distal
SI

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18
Q

SCHILLING TEST

A
Vit B12 gold Std
ing of vit B12 IM
24 hour urine 
< 10%
add IF
add Pancreatic enzymes
CT contrast?
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19
Q

coeliac spru e a/ w

A
Trype I DM
Ig A def
Dermatitis herpeteformis
Downs
Turners
20
Q

Coeliac spruce affects which part of SI

A

Proximal more

21
Q

. Anti tTg

A

most sensitive specific

antibody for coeliac sprue

22
Q

anti bodies coeliac sprue

A

Endomysial Ab
guinea pig tTG
human ttG
IGA IGG anti glia din

23
Q

Ix coeliac sprue

A

ab
biopsy
Reversal of changes *****

24
Q

Flat villi with crypt

hyperplasia

A

hallmark of coeliac sprue

25
Q

Indication for glucocorticoids in coeliac

A

Refractory

crisis

26
Q

Tropical sprue caused by

A

klebsiella pneumoniae
Enter obacter cloacae
E. coli

27
Q

Mononuclear cell infiltrate throughout the lamina

propria

A

Biopsy- tropical sprue

28
Q

Rx for tropical sprue

A

Doxycyclihe or tetra cycline (250 Qid)
x 6 months
Folic acid
Vit B 12

29
Q

Whipple s disease associations

A
migratory poly arthritis
pan card itis dementia supranuclear ophthalmoplegia
seizures
cerebellar ataxia 
polyserositis
hepatos planomegaly
30
Q

PAs positive macrophages

A

whipple’s disease

31
Q

Rx coeliac sprue

A

Inj ceftriaxone or
Inj meropenam
X2mweeks
or? Trimethoprim + sulphamethOxazole

32
Q

which IL helps in inhibition of

Immune system against food

A

1L- 10

33
Q

Co mmon feature UC CD

A
Age
se x -
Turners
Diarrhea
Anorexia
Nausea, vomiting
fever, weight loss
Euleaintes tinal manifestation
34
Q

gross blood in stool and mucous common in

A

UC

35
Q

smoking appendicectomy IBD

A

doubt?

36
Q

ocP and infection risk factor for which IBD

A

C D

37
Q

most commonly affected

site in uc

A

Rectum> sigmoid

38
Q

Rectal sparing IBD

A

CD

39
Q

Uc cannot affect

A

SI

40
Q

Trans mural 11BD

A

CD

41
Q

Collar button ulcer

A

uc

42
Q

Non caseating granuloma . IBD

A

CD

43
Q

strictures and skip lesion

which IBD

A

CD

44
Q

Pyoderma gangsinosun IBD

A

UC> CD

45
Q

Ocular manifestations of IBD

A

conjunctivitis
Anterior uveitis
episcleritis

46
Q

Ix IBD

A

ESR CRP Leucocytesis anemia
hypoalbuminea
PANCA* ,ASCA, OMP C ,I2 ,anti c - ….
Fecal cal protectin, lactoferrin

47
Q

Classification criteria

for uc

A

MAYO

TRUELOVE and WITTS