Growth Signals Flashcards
1
Q
Positive Growth Signals
A
1) CDK + Cyclin create a complex
2) Phosphorylate Rb to Rb + P
3) Rb changes shape, releases E2F
4) Cell division continues
2
Q
Negative Growth Signals:
A
1) CDK inhibitors block phosphorylation of Rb
2) So, E2F stays attached
3) Cell cycle halts
