Biochem Flashcards

1
Q

Define Acid

A

Donates a proton

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2
Q

Define Base

A

Accepts a proton

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3
Q

Weak Acid or Weak Base

A

Does not completely dissociate in a solution

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4
Q

Neutralization Reaction

A

Acid and base added together react to form a salt and water

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5
Q

Equilibrium constant

A

K

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6
Q

Dissociation constant

A

Kd

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7
Q

pH

A

Measure hydrogen activity
= -log [H+]

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8
Q

pKa

A

Measures the strength of an acid

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9
Q

pKa < 1

A

Measurement means this is a strong acid

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10
Q

pKa > 1

A

Measurement means this is a weak acid

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11
Q

Henderson-Hasselbalch equation

A

Used to calculate the pH of a solution given a known concentration of acid and a known concentration of base

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12
Q

Equation used for creating buffers

A

Henderson-Hasselbalch equation

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13
Q

Environmental sources of acidosis

A

Phosphate or sulfate compounds
Grain-enriched diet
Diabetes
Starvation
Toxin ingestion

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14
Q

Environmental sources of alkalosis

A

Fruits
Vegetables

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15
Q

Organs which regulate acids and bases in the body

A

Kidneys and lungs

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16
Q

What gets reabsorbed by the kidneys to balance pH?

A

Bicarbonate HCO3

17
Q

What is removed by the kidneys to be urinated?

A

Ammonium NH3
Protons H+

18
Q

Which salts are important to regulating pH in the body?

A

Sodium Na+
K+

19
Q

Why does phosphoric acid H3PO4 have 3 pKa’s?

A

Phosphoric acid H3PO4 has 3 hydrogens to donate

20
Q

Intrinsic buffers

A

Phosphate PO4
Proteins’ amino acids

21
Q

Extrinsic buffer

A

Converting H2CO3 to H20 and CO2

22
Q

The pKa of phosphate PO4 which meets physiological conditions

A

pKa 7.2

23
Q

Site of extrinsic buffering

A

The lungs