CBC Flashcards

1
Q

A CBC is typically performed using

A

an automated instrument that measures various parameters, including cell counts and the physical features of some of the cells.

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2
Q

A standard CBC includes the following

A
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3
Q

Red blood cell (RBC) count

A

is a count of the actual number of red blood cells in your blood sample.

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4
Q

Hemoglobin

A

measures the total amount of the oxygen-carrying protein in the blood, which generally reflects the number of red blood cells in the blood.

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5
Q

Hematocrit

A

measures the percentage of your total blood volume that consists of red blood cells.

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6
Q

Red blood cell indices provide information on the physical features of the RBCs:

A

Mean corpuscular volume (MCV) is a measurement of the average size of your red blood cells.
Mean corpuscular hemoglobin (MCH) is a calculated measurement of the average amount of hemoglobin inside your red blood cells.
Mean corpuscular hemoglobin concentration (MCHC) is a calculated measurement of the average concentration of hemoglobin inside your red blood cells.
Red cell distribution width (RDW) is a measurement of the variation in the size of your red blood cells.

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7
Q

The CBC may also includereticulocyte count

A

which is a measurement of the absolute count or percentage of newly released young red blood cells in your blood sample.

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8
Q

White blood cell tests

A

> White blood cell (WBC) count
is a count of the total number of white blood cells in your blood sample.

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9
Q

White blood cell differential

A

may be included as part of the CBC or may be done in follow up if the WBC count is high or low. The WBC differential identifies and counts the number of the five types of white blood cells present (neutrophils, lymphocytes, monocytes, eosinophils, and basophils). The individual count can be reported as an absolute count and/or as a percentage of total.

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10
Q

Platelet tests

A

platelet count
Mean platelet volume (MPV)
Platelet distribution width (PDW)

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11
Q

platelet count

A

the number of platelets in your blood sample

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12
Q

Mean platelet volume (MPV)

A

may be reported with a CBC. It is a measurement of the average size of platelets.

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13
Q

Platelet distribution width (PDW)

A

may also be reported with a CBC. It reflects how uniform platelets are in size.

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14
Q

CBC results that are outside the established reference intervals may indicate

A

the presence of one or more diseases or conditions. Typically, other tests are performed to help determine the cause of abnormal results.

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15
Q

Red blood cell indices

A

mean cell volume(MCV)
mean cell hemoglobin(MCH)
mean cell hemoglobin concentration(MCHC)

These indices can be calculated from the hemoglobin, hematocrit, and red blood cell count valuesalthough on automated analyzers, the MCV is usually measured directly.

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16
Q

mean cell volume(MCV)

A

A complete blood count includes measurements of the three red blood cell indices

17
Q

mean cell hemoglobin(MCH)

A

The average size of red blood cells, expressed in femtolitres

18
Q

mean cell hemoglobin concentration(MCHC)

A

The average amount of hemoglobin per red blood cell, expressed in picograms

19
Q

RBC indices and anemia

A

Evaluation of red blood cell indices is helpful in determining the cause of anemia

20
Q

microcytic anemia

A

Anemia with a low MCV

21
Q

macrocytic anemia

A

Anemia with a high MCV

22
Q

hypochromic anemia

A

Anemia with a low MCHC

23
Q

normochromic anemia

A

If anemia is present but the red blood cell indices are normal

24
Q

An elevated MCHC can also be a false result from

A

conditions like red blood cellagglutination (RBC clumping)
(which causes a false decrease in the red blood cell count, elevating the MCHC).

25
Q

Red blood cell distribution width

A
  • The red blood cell distribution width (RDW) reflects the degree of
    variation in size of red blood cells.
  • An elevated RDW represents increased variation in red blood cell
    size, a condition known asanisocytosis.
  • Elevated RDW can be due to nutritional anemiassuch asiron
    deficiency anemiaand anemia due toVitamin B12
  • A low RDW has no clinical significance.
26
Q
A