NSAIDS Flashcards
1
Q
What is the role of the COX enzymes
A
It converts arachidonic acid into prostaglandins, which are mediators of inflammation
2
Q
How do NSAIDs inhibit the COX enzyme?
A
They compete with arachadonic acid in the active site of COX
3
Q
Which COX inhibitor is the only one that is SELECTIVE
A
Celecoxib (Celebrex)
4
Q
Acetaminophen blocks which specific COX enzyme
A
COX3 - which is located mainly in the brain and not at the site of inflammation (Tylenol is not and anti-inflammatory)
