Drugs Flashcards

1
Q

what is salbutamol, how does it work and what is it used for

A

beta 2 adrenergic receptor agonist
adrenalin relaxes the bronchial smooth muscle
works quickly but effects only last an hour
used for asthma

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2
Q

example of an inhaled corticosteroid for asthma and how it works

A

beclometasone
reduces inflammation and reactivity of the pathways
used as prophylaxis

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3
Q

what is salmeterol and what is it used for

A

long acting beta 2 adrenergic receptor agonist
work the same as the short acting they just last longer

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4
Q

describe long acting muscarinic receptor agonists (with an example)

A

tiotropium
block acetylcholine receptors (monitored by parasympathetic nervous system)
take them to allow for bronchodilation
taken in asthma

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5
Q

What is theophylline

A

Used for asthma relief
Relaxes bronchial smooth and reduces inflammation
Has a narrow therapeutic range (toxic in excess)
Requires monitoring of bloods 5 days after starting treatment and 3 days after changing dose

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6
Q

What is maintenance and reliever therapy (MART)

A

Combination of inhaler containing low dose corticosteroid and a fast acting LABA (Long acting beta agonist)

Replaces all inhalers; used for prevention and rescue

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7
Q

Drugs which decrease serum potassium

A

(remember ALT)
Acetazolamide
loop diuretics
thiazide diuretics

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8
Q

Drugs which increase serum potassium

A

(remember AASPP)
ACE inhibitor
Angiotensin 2 receptor blockers
Spironalctone
Potassium sparing diuretics
potassium supplements (Sando-K)

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9
Q

Why does alcohol bingeing cause polyuria

A

can lead to ADH suppression in the posterior pituitary gland subsequently leading to polyuria

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10
Q

Metoclopramide
What is it
What is it used for
adverse effects
when it should be avoided

A

D2 receptor antagonist mainly used in management of nausea
other uses:
GORD
used in management of migraines

Adverse effects:
oculogyric crisis ( defined as spasmodic movements of the eyeballs into a fixed position, usually upwards)
Hyperprolactinaemia
tardive dyskinesia
Parkinsonism

Should be avoided in: bowel obstruction

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