ISE Cardio 2

Question 1

[ACS] patients with renal disease often have an elevated

Answer 1

c troponin T (15-50%)
where as c troponin I elevations are less common (<10%)

Question 2

most catastrophinc complication to fibrinolytic therapy

Answer 2

intracranial bleeding

Question 3

absolute contraindications to fibrinolytic thearpy

Answer 3

1. any prior ICH
2. known structural cerebral vascular lesions (e.g. AVM)
3. known intracranial neoplasm
4. ischemic stroke within 3 months
5. active internal bleeding (excluding mesnses)
6. suspected aortic dissection or pericarditis

Question 4

Some relative contraindications to fibrinolytic therapy

Answer 4

1. severe uncontrolled BP (>180/100)
2. Prior ischemic stroke >3 months
3. current use of anticoagulants with known INR >2-2
4. Known bleeding diathesis
5. recent trauma (past 2 weeks)
6. prolonged CPR (>10 mins)
7. Major surgery (<3 weeks)
8. recent internal bleeding (within 2-4 weeks
9. previously treated with streptokinase
10. pregnancy
11. active PUD