AKI staging systems

Question 1

RIFLE

RISK

Answer 1

creatinine: 1.5 x baseline, OR

GFR decreased by > 25%

UO < 0.5 mL/kg at least 6 hours

Question 2

RIFLE

INJURY

Answer 2

creatinine: baseline x 2

OR

GFR decreased by > 50%

UO < 0.5 ml/kg/hr (at least 12 hours)

Question 3

RIFLE

FAILURE

Answer 3

creatinine: baseline x 3

OR

GFR decreased by > 75%

OR

creatinine > 4.0 (with acute rise > 0.5 mg/dl)

UO < 0.3 ml/kg/hour (for at least 24 hours) OR anuria for at least 12 hours

Question 4

RIFLE

LOSS

Answer 4

complete loss of kidney function > 4 weeks

Question 5

RIFLE

ESRD

Answer 5

end-stage renal disease

> 3 months

Question 6

AKIN 1

Answer 6

creatinine: baseline x 1.5-2 (within 7 days)

OR

> 0.3 mg/dl increase (within 48 hours)

UO < 0.5 mL/kg (for at least 6 hours)

Question 7

AKIN 2

Answer 7

creatinine: 2-3 x baseline

UO < 0.5 ml/kg/hr (for at least 12 hours)

Question 8

AKIN 3

Answer 8

creatinine: >3x baseline

OR

creatinine > 4.0 mg/dl (with acute rise >0.5 mg/dl)

OR

initiation of RRT

UO < 0.3 ml/kg/hour (for at least 24 hours) OR anuria for at least 12 hours

Question 9

KDIGO 1

Answer 9

creatinine: 1.5-1.9 x baseline (within 7 days)

OR

> 0.3 mg/dl increase (within 48 hours)

UO < 0.5 mL/kg (at least 6 hours)

Question 10

KDIGO 2

Answer 10

creatinine: 2.0-2.9 x baseline

UO < 0.5 ml/kg/hour for at least 12 hours

Question 11

KDIGO 3

Answer 11

creatinine: >3x baseline

OR

creatinine > 4.0 mg/dl (with acute rise >0.3 mg/dl within 48 hours or 1.5 times baseline)

OR

initiation of RRT

UO < 0.3 ml/kg/hour (at least 24 hours) OR anuria for at least 12 hours

Question 12

IRIS AKI

Grade 1

Answer 12

creatinine < 1.6 mg/dL

nonazotemic AKI

• documented AKI (historical, clinical, laboratory, or imaging evidence of AKI, clinical oliguria/anuria, volume responsiveness

AND/OR

• progressive nonazotemic increase in creatinine by at least 0.3 mg/dl within 48 hours

AND/OR

• measured oliguria (<1 ml/kg/hour) or anuria over 6 hours

Question 13

IRIS AKI

Grade 2

Answer 13

creatinine 1.7-2.5 mg/dl

• documented AKI and static or progressive azotemia

AND/OR

• progressive azotemia: increase in creatinine by at least 0.3 mg/dl within 48 hours or volume responsiveness

AND/OR

• measured oliguria (<1 ml/kg/hour) or anuria over 6 hours

Question 14

IRIS AKI

Grade 3

Answer 14

creatinine 2.6-5.0 mg/dl

moderate to severe AKI:

• documented AKI and increasing severities of azotemia and functional renal failure

Question 15

IRIS AKI

Grade 4

Answer 15

creatinine 5.1 - 10.0 mg/dl

moderate to severe AKI:

• documented AKI and increasing severities of azotemia and functional renal failure

Question 16

IRIS AKI

Stage 5

Answer 16

creatinine > 10.0

moderate to severe AKI:

• documented AKI and increasing severities of azotemia and functional renal failure

Question 17

VAKI

Stage 0

Answer 17

creatinine increase < 150% from baseline

Question 18

VAKI

Stage 1

Answer 18

creatinine increase of 150-199% from baselines

OR

creatinine increase of 0.3 mg/dl from baseline

Question 19

VAKI

Stage 2

Answer 19

creatinine increase of 200-299% from baseline

Question 20

VAKI

Stage 3

Answer 20

creatinine increase of at least 300% from baseline

OR

absolute creatinine value > 4.0 g/dL