Central Nervous System Drugs

Question 1

CNS drugs are mostly used for psychiatric disorders like?

Answer 1

suppression of seizures, relief of pain, production of enesthesia

Question 2

We have a barrier that prevents the chemical that are potentially harmful from going to the brain but this same barrier can be an obstacle for therapeutic agents to reach the brain. What is the barrier called?

Answer 2

Blood Brain Barrier

Question 3

This type of adaptation to prolonged use of drug requires 2-4 weeks or 1 month of use for the drug to have enough time to modify itself so that patients can experience full therapeutic effects.

Answer 3

Increased Therapeutic Effect

Question 4

It is one of the special manifestations of CNS adaptation wherein the course of longer consumption of the CNS drug will result to decreased therapeutic response.

Answer 4

Tolerance

Question 5

It is a state that occurs when a patient abruptly discontinued taking the medicine which lead to withdrawal syndrome.

Answer 5

Physical Dependence

Question 6

It is a neurodegenerative condition characterized by tremor, rigidity, postural instability, and slowed movements.

Answer 6

Parkinson’s Disease

Question 7

These are drugs that block receptors for acetylcholine.

Answer 7

Anticholinergic Agents

Question 8

This type of drug goes through conversion to Dopamine in the brain in order to activate Dopamine receptors.

Answer 8

Levodopa

Question 9

This is another type of a drug for dopamine replacement which permits more levodopa to be transported and blocks the destruction of levodopa in the periphery.

Answer 9

Carbidopa

Question 10

What is COMT inhibitors?

Answer 10

Catechol-O-methyltransferase

Question 11

Can COMT Inhibitors and Carbidopa work without Levodopa? Yes or No.

Answer 11

No

Question 12

It’s an anti-viral drug that’s also used to treat measles and HIV in some cases. It also promotes the release of dopamine which is a result of its side effect.

Answer 12

Amantadine

Question 13

To prevent Tyramine Reaction to happen, we have to provide health teaching to our clients. Therefore, Tyramine rich foods should not be given along with what medications?

Answer 13

Levodopa and MAO-A Inhibitors

Question 14

When you use Amantadine with dopaminergic drugs it will cause what type of adverse effects?

Answer 14

Anticholinergic

Question 15

What are the dopaminergic drugs that causes orthostatic hypotension?

Answer 15

Amantadine, Bromocriptine, Ropinirole

Question 16

We need to avoid giving our patients high-protein meals because it causes what type of condition?

Answer 16

Constipation

Question 17

During constipation, our patient may engage in the Valsalva maneuver, in which the patient may strain themselves and cause hypertension that may lead to

Answer 17

Stroke

Question 18

What is the abnormal contraction or uncontrollable twitching of the eyelids?

Answer 18

Blepharospasm

Question 19

When a patient has signs of overdose, the doctor usually orders a TDM. What does TDM stands for?

Answer 19

Therapeutic Drug Monitoring

Question 20

It is a group of disorders that mark by excessive excitability of neurons and it has continuous or recurrent seizures.

Answer 20

Epilepsy