Chem- Krebs/etc/cori Flashcards

1
Q

What is the fuel for the krebs cycle

A

Acetyle CoA (made from the 2 pyruvate in glycolosis)

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2
Q

How does pyruvate change to acetyl CoA

A

pyruvate dehydrogenase

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3
Q

rate limiting step of krebs

A

isocitrate dehyrogenase

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4
Q

end prducts of Krebs

A

3 NADH
1FADH
1GTP
2C02

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5
Q

what do each NADH and FADH produce

A

NADH- 3 atps
FADH- 2 atps

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6
Q

Where can pros enter the krebs

A

SOFA
-succinayl CoA
Oxaloacetate
Fumerate
A ketogluterate

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7
Q

what are the 2 points fat can enter the krebs

A

A ketogluterate
succinyle Coa

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8
Q

How does nadh made in the cytosol pass into the mitochondria for the ETC

A

malate aspartate
glycerol 3 phosphate shuttles

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9
Q

How does the malate aspartate shuttle work

A

cytosolic oxaloacetate reduced by malate by NADH

malate crosses mito
reoxidizes to oxaloaceptate

(has to conervte to asparatete to cross back out)

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10
Q

How does the gyleroc 3 phos shuttle work

A

DHAP is reduced to G3P and enters the mito and reacts with FAD to make FADH

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11
Q

where does NADH enter the ETC

A

Complex I

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12
Q

Where does FADH enter the ETC

A

Complex II (succinate dehydrogenase complex w coenzyme q)

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13
Q

What happens at complex IV

A

copper is used to transfer electrons

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14
Q

What happens at complex V

A

ATP synthase
-Oxygen is electron acceptor and oxygen is consumed and ate generated

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15
Q

What inhibits cytochrome C

A

Cyanide and Carbon monoxide

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16
Q

What is the Cori cycle

A

the metabolic pathway that occurs in the liver and is used to prevent lactic acid build u (converts it back to pyretic acid then to glucose thru glucneogenesis)

17
Q

How much ATP does the cori cycle use

A

Uses 4 molecules of ATP

18
Q

What is the goals of the pentose phosphate shuttle (3)

A

fatty acid synthesis
Detoxification
protection from free rads

19
Q

What is the fuel for the pentose phosphate path and limiting enzyme

A

Cytosol
G6P

Glucose 6 phosphate dehydrogenase

20
Q

End result of pentose phosphate

A

2 NADH
Ribose (for nucleotide synthesis)

21
Q

what is the initial step in glycogenesis

A

Glycogen synthase (also rate limiting)

22
Q

What is the rate limiting of glycogenolysis

A

Glycogen phosphorylase A/B

23
Q

How is glycogenolysis regulated

A

Stimed by glucagon and epinephrin

Inhibited by insulin