Amitriptyline Flashcards
1
Q
What class of drugs is amitriptyline?
A
-Tricyclic antidepressant (TCA)
-Block reuptake of serotonin and noradrenaline in presynaptic terminals leading to increased concentrations of these neurotransmitters
2
Q
What is amitriptyline licensed to treat?
A
-Depression
3
Q
What are the known side effects of amitriptyline?
A
-Anti-cholinergic: sedation, postural hypotension, tachycardia / arrhythmias, blurred vision, dry mouth, constipation, urinary retention
-Toxic in overdose
4
Q
What is the recommended dose of amitriptyline?
A
50-200mg
