anatomy

Question 1

what is found in the portal triad

Answer 1

hepatic artery, portal vein and bile duct

Question 2

what cells stores vitamin A in the liver

Answer 2

hepatic stellate cells (ITO cells)

Question 3

where are hepatic stellate cells found

Answer 3

space of disse

Question 4

what are kuppfer cells and where are they found

Answer 4

they are marophages found within hepatic sinusoids

Question 5

how many hepatic veins are there

Answer 5

3 right midle and left they drain into the IVC

Question 6

what are the three ligaments found on the liver

Answer 6

coronary (top of liver)
falciform( down centre)
ligamnetum teres (round lig hanging off bottom)

Question 7

what is produced by oxyntic cells in GI tract

Answer 7

Ghrelin (hunger signal)
Oxyntomodulin (suppress apetite)

Question 8

role of CCK and where is it produced from

Answer 8

causes gall bladder to contract and release bile
produced from enteroendocrine cells

Question 9

what is produced form L-cells in GI tract

Answer 9

Peptide YY and GLP-1

Question 10

what direction does blood flow with regards to central lobular vein and portal triad

Answer 10

from portal triad towards central vein

Question 11

what type of cirrhosis is seen in alcoholics

Answer 11

micronodular

Question 12

what disease are mallory bodies most associated with

Answer 12

alcoholic liver disease

Question 13

treatemtn of severe alcoholic hepatitis

Answer 13

IV steroids

Question 14

diagnosis of non alcoholic fatty liver disease

Answer 14

enhanced liver fibrosis blood test (ELF test)

Question 15

what antibodies are hepatitis A, B and C

Answer 15

A- IgM
B- IgM
C - IgG

Question 16

what hepatitis is spread faecal orally

Answer 16

A

Question 17

what test is used to assess fibrosis of the liver

Answer 17

liver elastography

Question 18

what type of hepatitis tend to be chronic

Answer 18

hepatitis C

Question 19

what is the antibody assoc with PBC

Answer 19

AMA - anti mitochondrial antobodies

Question 20

who gets PSC men or women

Answer 20

men

Question 21

what is PSC

Answer 21

inflam of the intra and extra hepatic biliary dicts

Question 22

what is PBC

Answer 22

autoimmune attck against intra hepatic bile ducts

Question 23

what type of cancers are assoc with PSC

Answer 23

cholangiocarcinoma nd colon cancer

Question 24

is onion skinning fibrosis seen in PSC or PBC

Answer 24

PSC

Question 25

what antibodies are assoc with autoimmune hepatitis
name 4

Answer 25

smooth muscle antibody
anti nuclear antibody
LKM1
raised IgG

Question 26

in haemochromatosis what would the results of an iron study be ( transferrin, ferritin and TIBC)

Answer 26

raised transferring anf ferritin
low TIBC

Question 27

what gene is involved in Haemochromatosisi

Answer 27

HFE

Question 28

what stain identifies the HFE stain

Answer 28

Perls stain

Question 29

is haemochromatosisi dominant or recessive

Answer 29

recessive

Question 30

treatment of haemochromatosisi

Answer 30

venesection

Question 31

is wilsons recessive or dominant

Answer 31

autosomal recessive

Question 32

where does the copper accumulate in wilsons disease

Answer 32

liver and basal ganglia

Question 33

what would serum caerloplasmin levels do in wilsons

Answer 33

decrease

Question 34

what is caeruloplasmin

Answer 34

copper binding protein mutated in wilsons