Introduction to Biomarkets Flashcards

1
Q

What are the components of the “big picture” of Biomarkets(course)?

A

1) Market Structure & Strategy
- Market fundamentals
- The external environment
- Firm capabilities
- Firm Boundaries

2) Engaging with markets
- The Marketing Mix
- Life-cycle management
- Measuring succes

3) Specific Topics
- Regulation for Bio-pharmaceuticals
- Industrial Biotechnology markets

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2
Q

What is the definition of markets

A

A collection of buyers and sellers who transact over a particular product or product class

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3
Q

What different types of markets exist?

A

Product markets
Labor markets
Markets for information

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4
Q

What is indirect information flow?

A

Seller observes changes in buyer’s behavior.
Seller may observe “something is going wrong” –> adjusts as a result

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5
Q

What is direct information flow?

A

The buyer tells the seller directly what they want/need

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6
Q

What factors make up the market structure?

A
  • Number of firms in the markets
  • Ease to enter of leave the market
  • Ability to set prices
  • Ability of product differentiation
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7
Q

What characterizes competitive markets?

A
  • Firms product homogenous products
  • Market entry and exit is easy (many sellers and buyers)
  • Firms are price-takers: firm cannot influence price (if price increase, market share decrease)
  • No notable profits (no long term profits) –> if a firm start to make profit, there is a market entry opportunity for other firms to enther
  • Full information and no transaction costs

–> companies in general do not like these markets

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8
Q

What characterizes a monopolistic market?

A
  • Only one producer of good (no close substitutes)
  • Market entry is difficult –> monopolist holds prohibitive patetns
  • Monopolistic firms are price-setters
  • Substantial profits (price is set above marginal costs)
  • Lower demand than in competitive market
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9
Q

What characterizes oligopolistic markets?

A
  • Product differentiation is possible
  • Small group of firms in the market
  • Substantial entry barriers (e.g.very capital required such as aircraft)
  • Firms can set prices and affect rival’s actions; incentive to coordinate (allthough they are not allowed to do this, some do indirectly)
  • Price level is high and firms can generate profits
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10
Q

What characterizes monopolistic competition?

A
  • Products are differentiated (meaning quality of marketing plays a role)
  • Typically many firms lower market power
  • Free market entry
  • Firms set the prices (in similar fasion as a monopolist)
  • Spare capacity
  • Price level is high - but limited long-run profits (since free entry)
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11
Q

What is the definition of marketing?

A

Science and art of explorting, creating and delivering value to satisfy the needs of a target market at a profit.

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12
Q

What does marketing attempt to do?

A

Identify unfulfilled needs and desires.
Defines measures
Quantifies the size of the identified market and profit potential
Pinpoints which segments the company is capable of serving best
Designs and promotes appropriate products and services

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13
Q

Does pharma companies spend more money on R&D or Marketing?

A

Marketing. Due to the importance for sales.

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14
Q

What is the Bull-Whip effect?

A

Demand fluctuates as we move up the supply chain.
The effect is related to information flows: unclarity regarding the relevance of fluctuation leads to bigger changes further up in the supply chain.

Example: The distributor sees the increase and expands its purchase order with the manufacturer to anticipate increased requests from other retailers as well. The manufacturer increases its manufacturing run in anticipation of greater product requests in the future.

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15
Q

What does geographic buyer concentration refer to?

A

Differentiated marketing strategy based on geography

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16
Q

What is the 5-stage model of the consumer buying process?

A
  1. Problem recognition
  2. Information search
  3. Evaluation of alternatives
  4. Purchase decision
  5. Pospurchase behavior
17
Q

What caracterizes B2B marketing?

A
  • Few larger buyers that account for large sales volumes
  • Close supplier-customer relationships: Proposals, contracts, routines
  • Professional purchasers
  • multiple buying influences
  • multiple sales calls
  • low price-demand elasticity
  • derived demand: monitoring end- user markets important
  • High demand volatility (fluctuation, bull-whip effect)
  • Geographic buyer concentration
  • direct purchasing (no intermediaries)
18
Q

What characterizes B2C marketing?

A
  • Products more important than relationships
  • emotional considerations afffect buying process more strongly
  • Brands and status very important
  • Less sophisticated buyers
  • Sing step processes, depending on product (impulse purchase)
  • Intermediaries frequently with important role in selling process
19
Q

What is the buygrid framework?

A

A framework that describes B2B buying process.

Describes the major stages (buy-phases of the industrial buing process in relation to major buying situations (buyclasses)

20
Q

What are the major buyphases of the buygrid framework?

A
  1. problem recognition
  2. General need description
  3. Product specification
  4. Supplier research
  5. Proposal solicitation
  6. Supplier selection
  7. Order-routine specification
  8. Performance review
21
Q

What are the buyclasses of the buygrid framework?

A
  1. New Task
  2. Modified rebuy
  3. Straight rebuy
22
Q

What is the push versus pull effect?

A

Technology push is attempting to push a technology into a market

Market pull are consumers telling indirectly that there is a need for x i.e. unmet needs

23
Q

What are the differences between biologics and small molecule?

A
  • Route of administratrion: biologics are often IV vs. small molecule self admin
  • Regulation/approval: biologics produced in animals vs. small molecule synthetically
  • Manufacturing/developing: biologics take longer to develop
  • R&D: biologics are more complex to develop
  • Value based pricing: biologics often more expensive due to above factors - outcome based pricing
24
Q

What are the overlap of marketing an R&D in bio/pharma

A

Market related consideration early-on in new product development.

  • Disease-focused market research: size and dynamics
  • Identifying unmet needs and market potential for a product
  • Developing product vision and strategy: key attributes, value prop, differentiation from competitors
  • Market segments identification and positioning strategy
  • identify minimum clinical and pharma-economic outcome levels
  • Determination of product name, publication stray, identify key-opinion-leaders
  • continuous evaluation after launch (prices, usages, new indications?)
25
Q

What are the steps of drug approval?

A
  1. Preclinical resarch
  2. Clinical studies
  3. Completion and submission of NDA
  4. FDA review
  5. Post- market surveillance
26
Q

What is innovation vs. imitations in drug development?

A

Innovator: First in class drug, unique mechanism of action

Me-too drug: same/similar mechanism of action, typically improved efficacy, dosage forms etc

Generic drug : Once patent runs out, exact replication of small mol, facilitated approval proces (hatch-waxman act)

Biosimilars: generics in context of large molecules, imitating large mol struc, more challenging to scale up

27
Q

What are the marketing implications of biologics?

A
  • smaller target market, and implie adequate diagnostics
  • requires more science educa. sales reps
  • smaller sales force
  • Stronger proof of clinical efficacy needed; outcome-based pricing
  • systematic development, partnerships
  • intensive patient educations
  • less vulnerable to generic competition
  • additional costs for shipping and storing
28
Q

What is the relationship between stock return and profitability between biotech and pharma?

A

Higher degree of fluctuation in biotech, they either do really well or really poor.

29
Q

What is the main difference between stock return and profitability in biotech?

A

a company can have tangiable assets without having products on the market (no profit).
Successfull clinical trials has positive effect on stocks and become interesting for larger companies as acquisition target

30
Q

What is an orphan drug?

A

A drug targeting rare diseases.
<6/10,000(US) and <5/10,000 (EU)
Facilitated regulatory pathway and economic incentives such as market exclusivity is attractive (orphan drug act 1983 and rare disease act 2000)
The orphan pathway can sometimes be leveraged for accessing mainstream indications