16: Mucosal Immunity Flashcards

1
Q

What are the junctions between mucosal epithelial cells?

A

tight junction

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2
Q

IEL

A

intraepithelial lymphocyte

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3
Q

What do goblet cells produce?

A

mucins

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4
Q

What is the main isotype in the lower respiratory tract and genitalia?

A

IgG

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5
Q

What is the main isotype in the upper respiratory tract?

A

IgA

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6
Q

What lamellar bodies secrete?

A

defensins and cathelicidins

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7
Q

Which T cells live within the epideris?

A

CD8+ memory T cells

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8
Q

Which T cells live within the dermis?

A

CD4+ Trm cells

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9
Q

What is the function of Paneth cells?

A

secrete defensins and antimicrobial peptides

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10
Q

What are commensals typically resistant to?

A

defensins and IgA

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11
Q

What is transcytosis of IgA mediated by?

A

polyIg receptor

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12
Q

Abs for immune exclusion

A

IgA, IgM

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13
Q

Abs for immune elimination

A

IgE, IgG, IgM

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14
Q

M cells

A

act as regulated gates in epithelial barriers

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15
Q

Which T cells are more prominent in lamina propria lymphpcytes?

A

CD4+ and Treg cells

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16
Q

Which T cells are more prominent in lamina intraepithelial lymphpcytes?

A

CD8+ and gamma/delta T cells

17
Q

Which cells are more prominent in Peyer’s patches?

A

B cells, some Th cells

18
Q

What cells are more prominent in oral mucosal tissues?

A

CD4+ T memory cells