Exercise (L37)

Question 1

What is phosphocreatine?

Answer 1

Fast onsite fuel
- high energy phosphate compound
- provides enough energy for 100m sprint

Question 2

Under what circumstances is it used?

Answer 2

anaerobic

Question 3

What enzyme is involved in phosphocreatine breakdown?

Answer 3

Creatine kinase: takes phosphate and gives it to ADP => ATP

Question 4

What is the role of phosphocreatine in muscles?

Answer 4

Provides initial burst of energy

Question 5

How is it used and regenerated?

Answer 5

Phosphate group cleaved from phosphocreatine, added to ADP by Creatine kinase enzyme. Reverse processes for regeneration

Question 6

How are glycogen stores mobilised?

Answer 6

Mobilised to G1P by glycogen phosphorylase -> G6P -> fuel for anaerobic glycolysis

Question 7

What enzyme stimulates muscle glycogen breakdown? What is the mechanism (receptor stuff)?

Answer 7

Adrenaline
When adrenaline binds to beta adrenergic receptors on muscle cells binds, GTP used and G protein released from GPCR and can move to adenylate cyclase to make cAMP
- GTP released and regenerated
- cAMP builds up -> signal amplifies through rest of pathway = lots of glucose quickly