Chapter 11 :: Cellular Components of the Cutaneous Immune System

Question 1

A slower but more adaptive arm of the immune system that can respond to near limitless range of pathogens

Answer 1

Adaptive immune system

Question 2

Recognize peptide antigens in the binding pocket of MHC class II molecules and differentiate into effec- tor subsets that have broader and different immuno- logic functions

Answer 2

Naïve CD4+ T cells

Question 3

Main mediators of cell-mediated immunity.

Answer 3

TH1 cells

Question 4

Respond to repeated antigen challenges extremely rap- idly, often within hours of exposure—such as that seen in fixed drug eruptions

Answer 4

Tissue Resident (TRM)

Question 5

Birbeck granules with tennis racket shape
Express CD207

Answer 5

Langerhans Cells

Question 6

Have the ability to phagocytize large numbers of pathogens and kill intracellular bacteria

Answer 6

Macrophages

Question 7

Hallmark cell of acute inflammation secondary to their high mobility and are usually recruited to sites of injury within minutes

Answer 7

Neutrophils

Question 8

Profound role in all aspects of eosinophil development, and can by produced by both T-cells and mast cells

Answer 8

IL-5