Dosage Forms

Question 1

List the main 5 delivery routes of drugs…

Answer 1

1. Oral
2. Rectal and Vaginal
3. Topical and transdermal
4. Parenteral
5. Pulmonary

Question 2

Oral dosage forms…

Answer 2

Tablets
Capsules
Powders and granules
Solutions
Suspensions
Emulsions

Question 3

Rectal and Vaginal dosage forms…

Answer 3

Suppositories
Enemas
Foams
Pessories

Question 4

Topical and Transdermal dosage forms…

Answer 4

Creams
Ointments
Gels
Patches

Question 5

Parenteral dosage forms…

Answer 5

Injections
Infusions

Question 6

Pulmonary drug delivery systems…

Answer 6

Inhalers
Nebuliser
Electronic cigarettes

Question 7

What are disperse systems?

Answer 7

One phase is distributed throughout a second phase.
Two immiscible phases in contact

Question 8

What are colloids?

Answer 8

A two phase system of matter a type of mixture intermediate between homogeneous mixtures and heterogenous mixtures
<1micrometer

Question 9

What are the two physical types of colloids?

Answer 9

Phase colloid
Molecular colloid

Question 10

What are phase colloids?

Answer 10

Small droplets of particles of one substance are suspended in another.

Question 11

What are molecular colloids?

Answer 11

Macromolecules are dispersed in a continuous phase.

Question 12

What is the Tyndall effect of colloids?

Answer 12

Light beam is visible (scatter light)

Question 13

What is the Brownian motion effect of colloids.

Answer 13

Colloid particles are suspended
Liquid molecules in mixture

Question 14

What is the adsorption agent of colloids?

Answer 14

Reversible
Chemical is associated to the surface

Question 15

What are the dialysis properties of colloids?

Answer 15

Unequal rates of diffusion
Separation of suspended colloid particles
Semi Permeable membrane

Question 16

What are the electrophoresis properties of colloids?

Answer 16

Migration of charged particles
Surface dependant
Negative to positive

Question 17

What are the thixotropy properties of colloids?

Answer 17

Becomes fluid with agitation
Change orientation as a different use

Question 18

Types of colloids

Answer 18

Lyophobic= solvent hating
Lyophilic= solvent liking

Question 19

What is a sol?

Answer 19

A colloidal suspension of small solid particles in a continuous liquid medium

Question 20

What is a gel?

Answer 20

A colloidal suspension in which the liquid medium has become viscous enough to behave more or less like a solid.

Question 21

What are difference between a two phase system and one phase system of gels?

Answer 21

Two phase:
Lyophobic
Opaque
Form a 3D sponge like network
Flocculated small particles
Network for elongated molecules
One phase:
Lyophilic
Clear
Range of bases from liquids to solids
Crystalline and amorphous regions held by van der walls forces

Question 22

What are foams?

Answer 22

Gases dispersed in a liquid/solid

Question 23

What do defoamers/ anti foaming agents do?

Answer 23

Displaces surfactants at the air-water interface

Question 24

What is a suspension?

Answer 24

Course dispersion in which insoluble particles are dispersed within a liquid medium which is usually aqueous.

Question 25

what is an emulsion?

Answer 25

A ‘pseudo-stable’ dispersion of at least two immiscible liquids, one of which is dispersed throughout the other in the form of fine droplets (generally oil and water) stabilised by the presence of an emulsifying agent (known as emulsifier)